Publications by authors named "Giuseppe Bellagamba"

Article Synopsis
  • The paper presents a new method called MEPS-HPLC-DAD for simultaneously detecting 12 azole antifungal drugs in biological samples like human plasma and urine.
  • This method effectively separates these drugs in just 36 minutes and has been validated for various concentration ranges to ensure accuracy.
  • It is the first of its kind to combine these techniques for azole drug analysis and was successfully used to measure drug levels of itraconazole and miconazole after they were taken orally.
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In this work, the biological and chemical fingerprints of three extracts (ethyl acetate, methanol, and water) from two species ( and ) were investigated. Antioxidant, enzyme inhibitory, and cytotoxic activities were performed for the biological fingerprint. For the chemical characterization, total bioactive components, and individual phenolic components were determined using photometric and HPLC methods, respectively.

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Colour is the first organoleptic property that consumers appreciate of a foodstuff. In blueberry (Vaccinium spp.) fruits, the anthocyanins are the principal pigments determining the colour as well as many of the beneficial effects attributed to this functional food.

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In this study, we evaluated the nutraceutical potential of Juglans regia L. (a dietary supplement and food-additive) by evaluating the in-vitro anti-diabetic potential and by assessing the in-vivo anti-hyperglycaemic, anti-hyperlipidaemic, and organ-protective effects of freshly-dried and powdered leaves of J. regia L.

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The current study was carried out to evaluate multicomponent pattern, biological and enzymatic activities of seven Asphodeline taxa root extracts as useful ingredients, due to the fact that these plants are commonly used as traditional food supplements in Turkish regions. The extracts were characterized for free anthraquinones and phenolics to obtain a specific chemical fingerprint useful for quality control. These analyzes were coupled to biological and enzymatic activities in order to obtain comprehensive information of the natural product.

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We developed and validated an analytical method based on microextraction packed sorbent (MEPS) and high-performance liquid chromatography (HPLC) coupled to photodiode array (PDA) detector to simultaneously quantify multiple nonsteroidal anti-inflammatory drugs (NSAIDs) and fluoroquinolones (FLQs), which may provide as combination several adverse reactions in nephrology and neurology. The linearity range from LOQs (0.1 μg/mL) to 10 μg/mL, and LODs values were 0.

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Article Synopsis
  • The study focuses on two Turkish plant species, Asphodeline anatolica and Potentilla speciosa, to see how their nutrients can be useful in medicine and healthy foods.
  • Researchers used a special technique called HPLC-PDA to compare important compounds called phenolics and anthraquinones in these plants.
  • The results suggested that these plants could help create new medicines or healthy supplements due to their beneficial properties.
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