Reconstruction of retroauricolar surgical defect using the "jigsaw puzzle" advancement flap.

We present the case of a 55-year-old male patient who came to our attention because of a basal cell carcinoma of the right retroauricolar area, near the mastoid-auricle border. The tumor had a size of about 1.5 cm.

Comparison of quality of life between melanoma and non-melanoma skin cancer patients.

The impact of skin cancers on patients' health-related quality of life (HRQoL) is often overlooked, and direct comparisons between melanoma and non-melanoma skin cancer (NMSC) are rare. Objectives: The aim of this study was to compare HRQoL in patients with melanoma and NMSC. Participants were unselected, consecutive adult patients with a diagnosis of melanoma at the time of wide excision, or NMSC at the time of surgery.

Interleukin-17 and interleukin-22 promote tumor progression in human nonmelanoma skin cancer.

Interleukin-17 (IL-17) and IL-22 have been reported to play critical roles in autoimmunity and inflammation but information about their role in cancer is limited. In this study, we investigated the role of IL-17 and IL-22 in the progression of human skin basal-cell carcinoma (BCC) and squamous-cell carcinoma (SCC). We found that both tumor types are infiltrated with an high number of IL-17(+) and IL-22(+) T lymphocytes, as demonstrated by immunohistochemistry and by FACS analysis performed on peritumoral T-cell lines isolated from skin biopsies.

Erbium:YAG laser and cultured epidermis in the surgical therapy of stable vitiligo.

Objective: To induce complete and reproducible repigmentation of large "stable" vitiligo lesions by means of autologous cultured epidermal grafts using a rapid, simple, and minimally invasive surgical procedure.

Design: Achromic epidermis was removed by means of appropriately settled erbium:YAG laser, and autologous epidermal grafts were applied onto the recipient bed. Melanocyte content was evaluated by dopa reaction.