Publications by authors named "Giulio Savazzi"
Article Synopsis
- T cells are crucial for fighting viral infections and cancer, so effective delivery systems for therapeutics targeting T cells are important, but challenging due to T cells' nonphagocytic behavior.
- Researchers have found that natural glycogen nanoparticles (nanosugars) can engage T cells and release drugs without the need for complex receptor-targeting antibodies.
- Among different nanoparticle types, smaller and positively charged glycogen nanoparticles (BG NPs) demonstrate superior internalization and drug release capabilities, proving effective in reactivating latent HIV-1 in T cells and transfecting mRNA.
