Publications by Giuliana F Argentino

Publications by authors named "Giuliana F Argentino"

Page 1 of 1

Angiotensin II Regulates Mitochondrial mTOR Pathway Activity Dependent on Acyl-CoA Synthetase 4 in Adrenocortical Cells.

Katia E Helfenberger Giuliana F Argentino Yanina Benzo Lucía M Herrera Paola Finocchietto

Endocrinology

October 2022

Two well-known protein complexes in mammalian cells, mTOR type 1 and type 2 (mTORC1/2) are involved in several cellular processes such as protein synthesis, cell proliferation, and commonly dysregulated in cancer. An acyl-CoA synthetase type 4 (ACSL4) is one of the most recently mTORC1/2 regulators described, in breast cancer cells. The expression of ACSL4 is hormone-regulated in adrenocortical cells and required for steroid biosynthesis.

View Article and Find Full Text PDF

- Giuliana F Argentino's recent research primarily focuses on the role of the mTOR pathway in cellular processes such as protein synthesis and cell proliferation, with implications for cancer biology.
- Her study highlights the regulatory role of acyl-CoA synthetase type 4 (ACSL4) in the mTORC1/2 pathway, particularly in adrenocortical cells, suggesting its importance in steroid biosynthesis and hormone regulation.
- The findings contribute to understanding how hormonal regulation of ACSL4 activity might affect the dysregulation of the mTOR pathway in cancerous contexts, emphasizing the intersection between metabolism and cellular signaling in endocrine functions.

Publications by authors named "Giuliana F Argentino"

Angiotensin II Regulates Mitochondrial mTOR Pathway Activity Dependent on Acyl-CoA Synthetase 4 in Adrenocortical Cells.

Synopsis of recent research by authors named "Giuliana F Argentino"