Publications by authors named "Giulia Soggia"
Article Synopsis
- * New research highlights the role of cytoskeletal forces in remodeling nuclear membraneless compartments called biomolecular condensates, which are crucial for RNA processing and cell division, particularly in reproductive health.
- * The review explores the broader implications of this mechanical remodeling of nuclear condensates across various health and disease contexts, emphasizing its significance in reproduction, cancer, and premature aging.
Article Synopsis
- * Optogenetic stimulation shows that whisker movements can be activated in various cerebellar regions, with the paramedian lobule having the quickest response time, while Purkinje cells vary in how they encode whisker position and velocity during actions like protraction and retraction.
- * The findings indicate that both the cerebellar cortex and nuclei have a complex representation of whisker kinematics, predominantly focusing on velocity, which enhances our understanding of how the cerebellum contributes to coordinating
Approximately 50% of colorectal cancer (CRC) patients still die from recurrence and metastatic disease, highlighting the need for novel therapeutic strategies. Drug repurposing is attracting increasing attention because, compared to traditional de novo drug discovery processes, it may reduce drug development periods and costs. Epidemiological and preclinical evidence support the antitumor activity of antipsychotic drugs.
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