PAI-1 and protein C as early markers of veno-occlusive disease in patients treated for Wilms tumor.

Background: Hepatic veno-occlusive (VOD) disease has been described in hematopoietic stem cell transplantation (HSCT), solid tumors, and acute lymphoblastic leukemia. The incidence of VOD in Wilms tumor (WT) ranges from 1.2% to 8%.