Publications by authors named "Giulia Santi"
Positioning biologics in the treatment of IBD: A practical guide
Curr Res Pharmacol Drug Discov
April 2022
Article Synopsis
- The variety of biological therapies for inflammatory bowel disease (IBD) has significantly increased, with the number available doubling in the last decade and new treatments like interleukin 23p19 inhibitors being introduced.* -
- Properly positioning these advanced therapies based on factors such as clinical situation, effectiveness, and safety is essential for delivering personalized IBD treatment.* -
- This publication summarizes recent literature and expert insights to help integrate comparative efficacy data and patient demographics into clinical practice for better decision-making regarding biological therapies.*
Background: Long-standing ulcerative colitis has been associated with an increased risk of colorectal cancer (CRC). Current guidelines recommend endoscopic CRC screening after 8 years of disease duration. The objectives of our study were to assess the adherence to recommendations and the quality of endoscopic procedure in long-standing ulcerative colitis.
View Article and Find Full Text PDFThere is increasing evidence of white matter (WM) pathology in schizophrenia, but its role at the very early stage of the disorder remains unclear. In an exploration of WM microstructure in ultra-high risk (UHR) subjects and first episode schizophrenia (FES), 34 FES, 27 UHR and 26 healthy control (HC) subjects underwent a magnetic resonance imaging (MRI) tract based spatial statistics (TBSS) investigation. Whole brain fractional anisotropy (FA), mean diffusivity (MD), radial (RD) and axial diffusivity (AD) values were extracted.
View Article and Find Full Text PDFHere we presented a single electroencephalographic (EEG) marker for a neurophysiological assessment of Alzheimer's disease (AD) patients already diagnosed by current guidelines. The ability of the EEG marker to classify 127 AD individuals and 121 matched cognitively intact normal elderly (Nold) individuals was tested. Furthermore, its relationship to AD patients' cognitive status and structural brain integrity was examined.
View Article and Find Full Text PDFBackground: A possible and neglected concern in women with endometriosis undergoing IVF is the potential risk of progression of the disease. We set up a prospective study mainly aimed at evaluating the impact of IVF on endometriosis-related symptoms.
Materials And Methods: Women with surgical or echographic diagnosis of endometriosis and selected for IVF were included.
The impact of IVF procedures on endometriosis recurrence.
Eur J Obstet Gynecol Reprod Biol
January 2010
Objective: In infertile women with endometriosis requiring an in vitro fertilization (IVF) procedure, the potential risk of an IVF-related progression of the disease remains a matter of debate. Thus, since available data on this issue are scanty and controversial, an observational study has been herein conducted in order to clarify this issue.
Study Design: We recruited 233 women with endometriosis who underwent IVF cycles in our unit.
Background/aims: Limited information is available regarding the quantity of blood loss associated with uncomplicated transvaginal oocyte retrieval. The aim of the present study was evaluating the quantity of such a loss.
Methods: One hundred and fifty consecutive women undergoing oocyte retrieval were recruited.