Reliability of Total Serum IgE Levels to Define Type 2 High and Low Asthma Phenotypes.

High total IgE levels are weak predictors of T2 and have been reported in nonallergic asthma. Therefore, the role of total serum IgE (IgE) in the T2 phenotype is still debated. Objective: This study investigated the reliability of stratifying asthmatics into IgE and IgE within the T2 and T2 phenotypes.

The prevalence of antiphospholipid antibodies in women with late pregnancy complications and low-risk for chromosomal abnormalities.

Background: Antiphospholipid antibodies (aPL) are known to increase the risk of obstetrical complications. However, aPL significance and prevalence in women with late-onset pregnancy complications (LO-PC) need further clarification.

Objectives: To investigate the prevalence of aPL in a cohort of women who experienced LO-PC and to compare it with a cohort of uneventful pregnancies.