Publications by authors named "Giulia Mezza"
Antioxidants (Basel)
June 2020
Article Synopsis
- Matrix metalloproteinases (MMPs) are key players in tumor growth and spread, and the compound 4'-geranyloxyferulic acid (GOFA) shows promise for its anti-tumor and anti-inflammatory effects.
- In experiments with U937 and HCT116 cancer cells, GOFA was found to reduce abnormal cell growth and MMP-9 activity caused by lipopolysaccharide (LPS), leading to decreased cell migration.
- The study suggests that GOFA's ability to inhibit the ROS/ERK pathway and prevent apoptosis and senescence may make it a valuable therapeutic option to combat tumor metastasis.
