Publications by authors named "Giulia Maria Tronconi"
Perinatal asphyxia and hypothermic treatment from the endocrine perspective.
Front Endocrinol (Lausanne)
November 2023
Article Synopsis
- - Perinatal asphyxia significantly contributes to neonatal death and health issues, with therapeutic hypothermia being the standard treatment that reduces mortality and major developmental disabilities.
- - Endocrine-related problems, such as glucose and electrolyte imbalances or adrenal complications, can arise in infants experiencing perinatal asphyxia, potentially impacting their health outcomes.
- - Clinicians need to recognize the potential endocrine complications in asphyxiated infants to implement effective screening and timely interventions for improving overall outcomes.
Article Synopsis
- The study aimed to determine if patients with Hashimoto thyroiditis (HT) are more likely to develop thyroid nodules or cancer by analyzing 904 children/adolescents over a median follow-up of 4.5 years.
- A total of 174 thyroid nodules were found, with a 3.5% annual incidence rate, and 10 of these nodules were malignant, resulting in a 5.7% cancer prevalence among those with nodules.
- The findings suggest that while HT may influence the formation of thyroid nodules, it does not significantly increase the risk of thyroid cancer in children and adolescents.
Background: Linear growth and final height are reported as normal in congenital hypothyroid patients in the neonatal screening era.
Methods: We evaluated the final height in 215 patients with congenital hypothyroidism to assess if it improved over the last 2 decades.
Results: Final height (-0.
The aim of the replacement therapy with levothyroxine in congenital hypothyroidism (CH) is to correct hypothyroidism and ensure normal growth and neuropsychological development. Few data are available about the appropriate dose during childhood and early adolescence; therefore, we performed a multicenter observational study in a large population of patients with CH to assess the required levothyroxine dose to obtain euthyroidism. We recruited 216 patients with permanent CH classified into three groups (agenesia, ectopia, and in situ gland) on the basis of the thyroid imaging.
View Article and Find Full Text PDFAcquired autoimmune hypothyroidism is common in late childhood and adolescence but is very rare in the first 3 years of life. We report on three cases of autoimmune thyroiditis (AT) in young children who presented with constipation, decreased appetite, and increased hours of sleep. Our cases highlight that AT may remain undiagnosed for a long time in young children owing to the rarity of the disease.
View Article and Find Full Text PDFBackground: Thyrotropin-secreting pituitary adenomas (TSHomas) are an extremely rare cause of hyperthyroidism. Up to now there are only few cases reported in the pediatric age range. Thefirst therapeutic option is surgical resection, whereas medical treatment with somatostatin analogs has been reported only in cases wherein surgery was unsuccessful.
View Article and Find Full Text PDFBackground: Celiac disease (CD) is a gluten-dependent enteropathy. The current standard for diagnosing CD involves obtaining 4 biopsy samples from the descending duodenum. It has been suggested that duodenal bulb biopsies may also be useful.
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