Publications by authors named "Giulia Loffredo"
Article Synopsis
- * A study of 257 individuals from 71 families found that approximately 20% of gene mutation carriers developed aHUS, indicating low penetrance, especially among siblings (7.47 events per 1000 person-years) and offspring (6.29 events per 1000 person-years).
- * The findings suggest that the disease risk is significantly lower than previously thought and varies by family relationship, emphasizing the need for careful consideration of genetic variant classifications over time.
