Publications by authors named "Gita Alizadeh"
Background: Recent articles have explored the effect of worms on cancer cells. This review focused on various cell cultures employed to understand which cells are more commonly and less utilized.
Methods: The present review analyzed studies published between 2013 and 2023 to obtain information about different cell cultures used in cancer studies involving helminths.
Article Synopsis
- Fascioliasis is a parasitic infection caused by Fasciola species, affecting both humans and animals, yet current diagnostic methods remain under-validated despite advancements in treatment.
- This study aimed to compare the effectiveness of Real-Time PCR with indirect-ELISA to detect Fasciola hepatica infections, using a test group consisting of patients with known infections and others with different parasitic diseases or no infections.
- Results showed that 62.86% of the serum samples tested positive for F. hepatica, with both diagnostic methods exhibiting a high level of agreement (91.4% for ELISA and 99.2% for Real-Time PCR), confirming the reliability of these tests for diagnosing fascioliasis in humans
Article Synopsis
- The study compared two diagnostic methods, semi-nested PCR and indirect ELISA, for detecting human fasciolosis using 70 serum samples from suspected patients in Iran.
- Results showed that semi-nested PCR had a higher agreement rate (98.4%) compared to indirect ELISA (94.46%), with no false positives from other parasitic infections.
- The findings suggest that semi-nested PCR is a reliable confirmatory method and can be used to monitor patient treatment effectively.
Toxocariasis is a zoonotic parasitic disease caused by migrating nematode worms, species larvae, within tissues. MicroRNAs (miRNAs) are small RNA molecules that regulate gene expression at a post-transcriptional level. miRNA-based diagnostic biomarkers for toxocariasis are emerging, but there is limited information about the role of many miRNAs and a more detailed diagnostic evaluation of miRNA expression patterns is needed to understand their immunobiological function.
View Article and Find Full Text PDFToxocara is one of the most prevalent nematodes in Iran, which infect humans as an intermediate host. Infection complications result from the larva migration. Human toxocariasis prevalence was various in Iran according to the area of study and population.
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