Publications by authors named "Giselle Maria Petzinger"

Article Synopsis
  • The study investigates how pathologic perivascular spaces (PVS) in the brain relate to cognitive decline in Parkinson's disease (PD), focusing on specific cognitive areas over two years.
  • Researchers used MRI to measure PVS volume in different brain regions, combined with neuropsychological tests assessing various cognitive functions.
  • Results indicated that a higher PVS volume in the basal ganglia correlated with significant declines in attention, executive function, and overall cognitive performance in individuals with PD.
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Perivascular spaces (PVS), fluid-filled compartments surrounding brain vasculature, are an essential component of the glymphatic system responsible for transport of waste and nutrients. Glymphatic system impairment may underlie cognitive deficits in Parkinson's disease (PD). Studies have focused on the role of basal ganglia PVS with cognition in PD, but the role of white matter PVS is unknown.

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In this study, we explored the association between the personality traits, neuroticism and introversion, and risk of Parkinson disease (PD). A population-based cohort study was conducted using questionnaire data from the Swedish Twin Registry for twins born 1926-1958 (n > 29,000). Personality traits were assessed in 1973 by a short form of Eysenck's Personality Inventory.

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