Gestational diabetes and pre-pregnancy overweight: possible factors involved in newborn macrosomia.

Aim: Good glycemic control in gestational diabetes mellitus (GDM) seems not to be enough to prevent macrosomia (large-for-gestational-age newborns). In GDM pregnancies we studied the effects of glycemic control (as glycosylated hemoglobin [HbA1c]), pre-pregnancy body mass index (PP-BMI) and gestational weight gain per week (GWG-W) on the frequency of macrosomia.

Methods:   We studied 251 GDM pregnancies, divided into two groups: PP-BMI<25.