Publications by authors named "Gisele Wakim"

Complex regional pain syndrome (CRPS) is a chronic neuropathic pain disorder often following trauma, associated with severe pain and autonomic disturbances in the affected limbs. Managing CRPS is challenging due to the lack of FDA-approved medications, often requiring off-label treatments. Traditional options like nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids show limited efficacy, while adjunctive treatments such as gabapentin, antidepressants, and bisphosphonates are increasingly favored.

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Article Synopsis
  • - Protamine sulfate is used to reverse the effects of unfractionated heparin during surgeries but can cause severe reactions like anaphylaxis.
  • - A 77-year-old male experienced serious side effects, including low blood pressure and rapid heart rate, after receiving protamine during a carotid endarterectomy.
  • - The case stresses the need for careful monitoring when administering protamine, especially for high-risk patients, and suggests looking into alternative methods for reversal to improve safety.
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Tracheoesophageal fistula develops in 5 % to 15 % of patients with esophageal cancer. Metal stent placement can be used for treatment. Stent placement can result in aspiration, hemorrhage, perforation, migration, and pneumonia.

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