Publications by authors named "Gisela Reising-Ackermann"
Article Synopsis
- The study investigates heterochromatic variants of chromosome 9 through the largest molecular cytogenetic research involving over 300 carriers, revealing 17 distinct variants, five of which were previously unreported.
- A new 3-color FISH probe-set allowed researchers to classify 21 out of the 24 known heteromorphic patterns, with pericentric inversions being the most common.
- The findings indicate that certain variants occur more frequently in Western Europe compared to Eastern Europe, and there is no strong connection established between these variants and infertility.
Thirty-two new cases with small supernumerary marker chromosomes detected in connection with fertility problems: detailed molecular cytogenetic characterization and review of the literature.
Marina Manvelyan Mariluce Riegel Monica Santos Carme Fuster Franck Pellestor Gisela Reising-Ackermann
Int J Mol Med
June 2008
Thirty-two patients with fertility problems were identified as carriers of small supernumerary marker chromosomes (sSMC). Molecular cytogenetic techniques were used to characterize their chromosomal origin. Together with the other cases available in the literature 111 sSMC cases have now been detected in connection with fertility problems in otherwise clinically healthy persons and characterized for their genetic content.
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