Publications by authors named "Gisela Neto"
Chronic kidney disease (CKD) in children, from birth to late adolescence, is a unique and highly challenging condition that requires epidemiological research and large-scale, prospective cohort studies. Since its first launch in 2007, the European Society for Paediatric Nephrology/European Renal Association (ESPN/ERA) Registry has collected data on patients on kidney replacement therapy (KRT). However, slowing the progression of CKD is of particular importance and thus the possibility to extend the current registry dataset to include patients in CKD stages 4-5 should be a priority.
View Article and Find Full Text PDFBackground: The guidelines for training of patients and caregivers to perform home peritoneal dialysis (PD) uniformly include recommendations pertaining to the prevention of peritonitis. The objective of this study conducted by the International Pediatric Peritoneal Dialysis Network (IPPN) was to investigate the training practices for pediatric PD and to evaluate the impact of these practices on the peritonitis and exit-site infection (ESI) rate.
Methods: A questionnaire regarding details of the PD program and training practices was distributed to IPPN member centers, while peritonitis and ESI rates were either derived from the IPPN registry or obtained directly from the centers.
Article Synopsis
- The study examines the timing of dialysis initiation in children with end-stage kidney disease (ESKD) to understand its impact on clinical outcomes, focusing on a cohort of 2,963 children from 21 European countries.
- There are two groups analyzed based on estimated glomerular filtration rate (eGFR) at the start of dialysis: early starters (eGFR ≥8 mL/min/1.73 m²) and late starters (eGFR <8 mL/min/1.73 m²), with no significant differences found in survival or access to transplantation between the two.
- The results indicate that starting dialysis early does not provide significant clinical benefits; however, attention should be given to cardiovascular risk factors like hypertension when