Incidence and determinats of augmented renal clearance in traumatic brain injury: A prospective observational study.

Purpose: To characterize the incidence, timing, and predictors of augmented renal clearance (ARC) in patients with traumatic brain injury (TBI).

Materials And Methods: In 61 patients with TBI, creatinine clearance (CrCl) was prospectively measured from urine samples, over seven days. ARC was defined as a CrCl >130 mL/min/1.

Comparative skin penetration profiles of formulations including ultradeformable liposomes as potential nanocosmeceutical carriers.

Background: Ultradeformable liposomes are promising carriers for cosmeceutical actives as they can be loaded with molecules of different polarities, and they present unique penetration properties.

Aims: While those features have already been tested, we wanted to know whether their special penetration properties could be maintained after incorporation in diverse cosmetic vehicles, including commercial products already in the market.

Methods: Ultradeformable liposomes loaded with a lipophilic and a hydrophilic fluorescent probe were prepared by lipid film resuspension, followed by extrusion and incorporation to different vehicles and commercial products.

[Serum levels of interferon-gamma and interleukine-10 in anemic children with vitamin A deficiency].

Studies done with human and animals have shown that the diminished vitamin A intake can produce anemia, but the ethiopathogenic mechanism hasn't been known due to the few studies about the complex interactions between micronutrients deficiencies, immune system and cytokine productions. The objective of the present study was to analyze the serum concentration of IFN-gamma and IL-10 in anemic and non anemic children according to vitamin A nutritional status. A descriptive study of 53 euthrophic children, without infectious diseases (45-77 month old; 29 girls, 24 boys), living in a slum in Maracaibo-Venezuela.

[Serum values of cytokines in children with vitamin A deficiency disorders].

Vitamin A Deficiency Disorders (VADD) have been associated with alterations of cellular differentiation, regulatory functions of the immune system and increased children morbidity and mortality rates due to acute respiratory and intestinal infections. The aim of the present study was to determine serum concentrations of Thl-Th2 cytokines in VADD children. The sample consisted of 138 children (F=72; M=66; 4-7 y old) living in slums in Maracaibo, Venezuela, with an adequate nutrition assessed by clinics and anthropometry.

[Plasma amino acids profile of healthy pregnant adolescents in Maracaibo, Venezuela].

One hundred female adolescents (13-18 y) were clinical and anthropometrically studied to select only those with adequate nutrition. Most adolescents belonged to IV socio-economic stratum families (worker class). Height, weight, age, body mass index and medial arm circumference were used as anthropometric parameters.

[Vitamin A deficiency and the anthropometric nutritional status of urban and rural marginalized children in the state of Zulia, Venezuela].

The present transversal study was carried out to estimate the prevalence of both vitamin A deficiency (VAD) and protein-energy malnutrition among children (24 to 85 months) from three urban slums (n = 173) in Maracaibo city, Zulia State, Venezuela and a rural slum area (n = 34), vieinal to Maracaibo, by measuring serum retinol and z score of anthropometric indices Height//Age (H//AZ); Weight//Age (W//AZ) and Weight//Height (W//HZ), compared to NCHS-WHO reference values. The Graffar's methodology adapted to Venezuela by Méndez Castellano (1986) confirmed the underprivileged socio-economic condition of the children population. For serum retinol analysis, peripheral venous blood was drawn and serum was treated according to the Bieri et al.