Publications by authors named "Giri M"

Background: The relationship between albumin-corrected anion gap (ACAG) and in-hospital mortality in critically ill patients with COPD remains unclear.

Objective: This study investigated the association between ACAG levels and the risk of in-hospital mortality in critically ill patients with COPD.

Design: A retrospective cohort study.

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Background: Sepsis-induced acute kidney injury (AKI) is difficult to prevent because most patients are diagnosed after they develop it. Standard serum and urine creatinine levels are insensitive and nonspecific for detecting kidney injury in its early stages. Glutathione S-transferase (GST) has received little attention as a biomarker in AKI.

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Background Although laparoscopic surgery is becoming more common, its anesthetic management poses challenges due to hemodynamic fluctuations. Dexmedetomidine has shown promise in mitigating these responses. In this study, we compared the effects of three different infusion doses of dexmedetomidine (0.

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Stomata, the small pores on the surfaces of leaves and stems, are crucial for gas exchange in plants and also play a role in defense against pathogens. The stomatal movement is not only influenced by surrounding light conditions but also by the presence of foliar pathogens. To put it more crisply, certain light wavelengths such as blue or strong red light, cause stomatal opening, which tragically makes it easier for bacteria to enter through opened stomata and causes disease progression in plants.

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  • This study investigates how temperature and duration of cardiopulmonary bypass (CPB) affect cerebral oxygen saturation during open-heart surgeries and links it to neurological outcomes.
  • It involved 60 patients aged 18-60, using near-infrared spectroscopy to monitor cerebral saturation and assessing cognitive function and neurological status post-surgery.
  • Results showed that longer CPB duration correlated with lower cerebral saturation, and lower saturation was linked to early cognitive decline, although its effect on later cognitive issues remains uncertain.
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Background: Several studies have shown a potential relationship between triglyceride-glucose index (TGI) and asthma. However, limited research has been conducted on the relationship between TGI and fractional exhaled nitric oxide (FeNO).

Methods: A total of 1,910 asthmatic individuals from the National Health and Nutrition Examination Survey (NHANES) database were included in this study.

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  • The study examines the link between heavy metal exposure and mortality in asthmatics, focusing on the effects of blood levels of selenium and manganese.
  • It found that higher blood selenium levels are inversely associated with mortality, while higher manganese levels correlate with increased mortality.
  • The research suggests that optimizing dietary selenium and managing manganese exposure could enhance asthma outcomes, highlighting the importance of balancing these metal levels for better health.
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Carbon dioxide (CO) is one of the most abundant greenhouse gases in Earth's atmosphere and responsible for global warming. Therefore, aerial CO capture and sequestration has become a major task for human community. Though several adsorbents for CO including activated carbon, zeolites, metal-organic frameworks (MOFs), and other surface-modified porous materials are well developed, the supramolecular approaches using synthetic hydrogen-bonding receptors are less explored.

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Background: Currently, there is limited research on the correlation between protein levels in the body and asthma. We used data from the NHANES to explore the relationship of dietary protein, serum albumin, with mortality in individuals with asthma to better understand their impact on asthma.

Method: This investigation involved 3005 individuals with asthma from the NHANES dataset.

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  • The study aimed to systematically investigate symptoms associated with commonly prescribed homeopathic medicines using Bayesian statistics for more accurate likelihood ratios (LR).
  • Conducted over 21 months with 1,954 patients, the research utilized the ORIDL scale to measure treatment outcomes and calculated LRs for four specific symptoms linked to six selected homeopathic remedies.
  • Findings revealed high LR+ scores for symptoms like "dyspepsia from business anxiety" and "burning pain relieved by heat," supporting existing homeopathic literature, but emphasized the need for further research to confirm results in larger populations.
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  • The study investigates how the blood urea nitrogen to creatinine ratio (BCR) relates to in-hospital mortality risk in ICU patients diagnosed with venous thromboembolism (VTE).
  • Using data from the MIMIC-IV database, researchers found that a BCR cut-off value of 26.84 could help predict mortality, revealing a significant difference in death rates between high BCR (22.6%) and low BCR (12.2%) groups.
  • The analysis indicated that patients with higher BCR levels had a 77.7% increased risk of in-hospital mortality, suggesting that BCR can be a valuable prognostic tool in critically ill VTE patients.
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  • - The study investigates the relationship between serum lipid levels and all-cause mortality in adults with asthma, as most research has focused on lipid profiles without considering their effect on mortality.
  • - Analyzing data from 3,233 asthma patients, the research found that higher levels of low-density lipoprotein cholesterol (LDL-C) were associated with a 17% reduced risk of death, while other lipids like high-density lipoprotein cholesterol (HDL-C), total cholesterol, and triglycerides showed no significant association with mortality.
  • - The conclusion emphasizes that in American asthma patients, LDL-C levels are significantly tied to lower mortality rates, suggesting a protective effect, while other serum lipids do not appear to independently influence
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Background: Presently, numerous studies have indicated that protein consumption and levels of blood albumin serve as important biomarkers for a range of respiratory illnesses. However, there have been few investigations into the correlation between protein consumption, serum albumin, and asthma.

Methods: Our analysis incorporated 2509 asthmatics from the 2011-2018 NHANES dataset.

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Background: Presently, the majority of investigations primarily evaluate the correlation between triglyceride-glucose index (TyGI) with lung diseases, such as asthma. However, they did not delve into the correlation between TyGI and inflammatory responses related to the disease. Few studies have explored the association between TyGI and blood eosinophil count (BEOC).

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Dermatophytosis is a cutaneous infection that is able to degrade the keratinized tissues of the animal/human body, like skin, nails, and hair, causing chronic or subacute infection with the contact of some specific fungal strains. Trichophyton mentagrophytes are the most potential fungal pathogen causing dermatophytoses. The present study focuses on computationally based in silico antifungal activity of selected phytocompounds of Leucas aspera (Willd.

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Many children in immigrant families may qualify for legal protection-for themselves if unaccompanied, or as a derivative on parents' claims-on humanitarian grounds related to persecution or forced migration. Pediatric providers can offer a spectrum of multidirectional medical-legal supports to increase access to medical-legal services and support children who are undocumented or in mixed-status families. These activities can include providing trusted information, incorporating screening for health-related social needs, establishing networks for multidirectional referrals, and providing letters of support for legal protection.

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This review article explores the intricate role, regulation, and signaling mechanisms of WRKY TFs in response to biotic stress, particularly emphasizing their pivotal role in the trophism of plant-pathogen interactions. Transcription factors (TFs) play a vital role in governing both plant defense and development by controlling the expression of various downstream target genes. Early studies have shown the differential expression of certain WRKY transcription factors by microbial infections.

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Calix[4]pyrroles are an important class of oligopyrrolic macrocycles and have found applications in many diverse fields including anion recognition. To modulate the properties of the calix[4]pyrrole, several structural modifications are realized. The core-expansion has attracted extra attention as it provides larger cavity-size compared to parent calix[4]pyrrole(s).

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Background: So far, quite a few studies have revealed that systemic iron levels are related to asthmatic inflammatory reactions. And most studies have focused on the correlation between systemic iron levels and asthma, with inconsistent findings. Yet, few studies have investigated the connection between serum iron and blood eosinophil counts.

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Biosensors, in particular nanobiosensors, have brought a paradigm shift in the detection approaches involved in healthcare, agricultural, and industrial sectors. In accordance with the global expansion in the world population, there has been an increase in the application of specific insecticides for maintaining public health and enhancing agriculture, such as organophosphates, organochlorines, pyrethroids, and carbamates. This has led to the contamination of ground water, besides increasing the chances of biomagnification as most of these insecticides are non-biodegradable.

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Background: A growing number of research strongly suggest that metabolic syndrome and dyslipidemia contribute to the establishment of a pro-inflammatory state in asthma, according to accumulating data. However, the majority of recent research has focused on the association between lipids and asthma in children and adolescents, with contradictory findings. Consequently, we analyzed the relationship between serum lipid and blood eosinophil counts using data from the NHANES in the USA.

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Inflammatory bowel disease (IBD) is a group of chronic digestive tract inflammatory conditions whose genetic etiology is still poorly understood. The incidence of IBD is particularly high among Ashkenazi Jews. Here, we identify 8 novel and plausible IBD-causing genes from the exomes of 4453 genetically identified Ashkenazi Jewish IBD cases (1734) and controls (2719).

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Background: To date, many researches have investigated the correlation of folate and asthma occurrence. Nevertheless, few studies have discussed whether folate status is correlated with dis-ease severity, control or progression of asthma. So, we explored the correlation of serum folate and blood eosinophil counts in asthmatic adults to gain the role of folate in the control, progression, and treatment of asthma.

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Background: Assessment of lung function is essential for the early screening chronic airway diseases (CADs). Nevertheless, it is still not widely used for early diagnosing CADs in epidemiological or primary care settings. Thus, we used data from the US National Health and Nutrition Examination Survey (NHANES) to discuss the relationship between the serum uric acid/serum creatinine (SUA/SCr) ratio and lung function in general adults to gain the role of SUA/SCr in early assessment of lung function abnormalities.

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