Knee joint proprioception: a comparison between female intercollegiate gymnasts and controls.

The role of proprioception as a protective mechanism has gained interest in recent years. From the clinical standpoint, several studies have dealt with ways to enhance proprioception following surgery and during rehabilitation. If kinesthesia (ability to detect passive motion) can be enhanced as a consequence of long-term athletic training, such training must be included as a part of the rehabilitation process to protect the patient from reinjury.

Analysis of agonism at functional prejunctional alpha 2-adrenoceptors of rat vas deferens using operational and null approaches.

The alpha 2-adrenoceptors located prejunctionally on the postganglionic neurons that innervate the smooth muscle of the prostatic portion of the rat vas deferens were examined. For this purpose, three imidazolidine derivatives (structurally related to clonidine) were studied for their effects on twitch contractions elicited by electrical field stimulation of this tissue. In this study, operational model-fitting and the nested hyperbolic method were used to analyse the effects of irreversible receptor alkylation by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) on the alpha 2-adrenoceptor-mediated effects of clonidine (2-[2,6-dichlorophenylimino]imidazolidine) in stimulated vas deferens.

Theoretical studies on the histamine H2 receptor: molecular mechanism of action of antagonists.

The previously defined sites in the histamine H2 receptor model [Mol. Pharmacol. 40:980-987 (1991)] were used to elucidate the pharmacological mechanism of action of compounds that act as antagonists at the receptor.

Theoretical studies on the histamine H2 receptor: construction of a receptor model based on the structural properties of dimaprit and N alpha-guanylhistamine.

A histamine H2 receptor model was constructed based on the receptor sites previously proposed by Weinstein et al. [Mol. Pharmacol.