Predictive model of explosive detonation parameters from an equation of state based on detonation velocity.

This article describes a predictive model of explosive detonation velocity and pressure based on first-order approximation of the detonation velocity equation. Detonation pressure was calculated from equations derived from the ideal detonation theory since that pressure is functionally related to detonation velocity. In the model calibration process, several product formation hierarchies were explored, with the best results yielded by the Kamlet and Jacobs (KJ) hierarchy.

A comparative analysis of health surveillance strategies for administrative video display terminal employees.

Background: The objective of this study was to develop a strategy to optimize medical health surveillance protocols for administrative employees using video display terminals (VDTs). A total of 2453 medical examinations were analysed for VDT users in various sectors. From these data, using Bayesian statistics we inferred which factors were most relevant to medical diagnosis of the main disorders affecting VDT users.

Anomalous material-dependent transport of focused, laser-driven proton beams.

Intense lasers can accelerate protons in sufficient numbers and energy that the resulting beam can heat materials to exotic warm (10 s of eV temperature) states. Here we show with experimental data that a laser-driven proton beam focused onto a target heated it in a localized spot with size strongly dependent upon material and as small as 35 μm radius. Simulations indicate that cold stopping power values cannot model the intense proton beam transport in solid targets well enough to match the large differences observed.

A Bayesian assessment of occupational health surveillance in workers exposed to silica in the energy and construction industry.

Medical records generated during occupational health surveillance processes have large amounts of unexploited information that can help to reduce silica-related health risks and many occupational diseases. The methodology applied in this study consists in analyzing through machine learning techniques a database with 70,000 medical examinations from workers in the energy and construction industry in Spain. First, a general unsupervised Bayesian model is built and node force analysis is used to identify the factors with the greatest impact on the worker's health surveillance process.

Post-operative stress hyperglycemia is a predictor of mortality in liver transplantation.

Background: A significant association is known between increased glycaemic variability and mortality in critical patients. To ascertain whether glycaemic profiles during the first week after liver transplantation might be associated with long-term mortality in these patients, by analysing whether diabetic status modified this relationship.

Method: Observational long-term survival study includes 642 subjects undergoing liver transplantation from July 1994 to July 2011.

How high energy fluxes may affect Rayleigh-Taylor instability growth in young supernova remnants.

Energy-transport effects can alter the structure that develops as a supernova evolves into a supernova remnant. The Rayleigh-Taylor instability is thought to produce structure at the interface between the stellar ejecta and the circumstellar matter, based on simple models and hydrodynamic simulations. Here we report experimental results from the National Ignition Facility to explore how large energy fluxes, which are present in supernovae, affect this structure.

Grain-size-independent plastic flow at ultrahigh pressures and strain rates.

A basic tenet of material science is that the flow stress of a metal increases as its grain size decreases, an effect described by the Hall-Petch relation. This relation is used extensively in material design to optimize the hardness, durability, survivability, and ductility of structural metals. This Letter reports experimental results in a new regime of high pressures and strain rates that challenge this basic tenet of mechanical metallurgy.

Time-resolved compression of a capsule with a cone to high density for fast-ignition laser fusion.

The advent of high-intensity lasers enables us to recreate and study the behaviour of matter under the extreme densities and pressures that exist in many astrophysical objects. It may also enable us to develop a power source based on laser-driven nuclear fusion. Achieving such conditions usually requires a target that is highly uniform and spherically symmetric.

Prehospital Sepsis Project (PSP): knowledge and attitudes of United States advanced out-of-hospital care providers.

Introduction: Severe sepsis and septic shock are common and often fatal medical problems. The Prehospital Sepsis Project is a multifaceted study that aims to improve the out-of-hospital care of patients with sepsis by means of education and enhancement of skills. The objective of this Project was to assess the knowledge and attitudes in the principles of diagnosis and management of sepsis in a cohort of United States out-of-hospital care providers.

Assembly of high-areal-density deuterium-tritium fuel from indirectly driven cryogenic implosions.

The National Ignition Facility has been used to compress deuterium-tritium to an average areal density of ~1.0±0.1 g cm(-2), which is 67% of the ignition requirement.

Precision shock tuning on the national ignition facility.

Ignition implosions on the National Ignition Facility [J. D. Lindl et al.

Prognostic utility of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI).

Background: We sought to evaluate the test characteristics of the acute cardiac ischemia time-insensitive predictive instrument (ACI-TIPI) in relation to 30-day major adverse cardiac events (MACE) among patients who presented to the Emergency Department with symptoms suggestive of an acute coronary syndrome. We then examined the test characteristics of various dichotomous ACI-TIPI cut points.

Methods: We prospectively recruited a cohort of Emergency Department (ED) patients with acute chest pain at two urban university hospitals between June and September 2006.

Demonstration of ignition radiation temperatures in indirect-drive inertial confinement fusion hohlraums.

We demonstrate the hohlraum radiation temperature and symmetry required for ignition-scale inertial confinement fusion capsule implosions. Cryogenic gas-filled hohlraums with 2.2 mm-diameter capsules are heated with unprecedented laser energies of 1.

Is consent "informed" when patients receive care from medical trainees?

Objectives: Medical care requires consent and consent requires information. Prior studies have shown that patients are poorly informed about the medical training hierarchy. The authors assessed the impact of "informed" on "consent," by assessing willingness to be seen by trainees before and after information about trainee's credentials.

Knowledge and attitudes of the out-of-hospital emergency care consumers in Santo Domingo, Dominican Republic.

Introduction: Prehospital emergency services are a vital public service, and consumer access to the system is an important factor in their use. The Dominican Republic recently experienced "the epidemiological transition" leading to increased morbidity and mortality secondary to traumatic and cardiac conditions--thus, increasing the need for prompt and adequate delivery of emergency medical care.

Methods: A survey was administered to 90 subjects from diverse backgrounds, all living in Santo Domingo.

Twenty-five years of violence: the epidemiology of terrorism in South America.

Introduction: Terrorism is a global public health burden. South Americans have been victims of terrorism for many decades. While the causes vary, the results are the same: death, disability, and suffering.

Laser heating of solid matter by light-pressure-driven shocks at ultrarelativistic intensities.

The heating of solid targets irradiated by 5 x 10(20) W cm(-2), 0.8 ps, 1.05 microm wavelength laser light is studied by x-ray spectroscopy of the K-shell emission from thin layers of Ni, Mo, and V.

Precision and reliability of the Glasgow Coma Scale score among a cohort of Latin American prehospital emergency care providers.

Introduction: The Glasgow Coma Scale (GCS) is the standard measure used to quantify the level of consciousness in patients with head injuries. Rapid and accurate GCS scoring is essential for adequate assessment and treatment of critically sick and injured patients. This study sought out to determine the precision and reliability of the GCS among a cohort of Latin American Critical Care Transport Providers.

Predictive effect of out-of-hospital time in outcomes of severely injured young adult and elderly patients.

Introduction: The importance of accessing care within the first hour after injury has been a fundamental tenet of trauma system planning for 30 years. However, the scientific basis for this belief either has been missing or largely derived from case series from trauma centers. This study sought to determine the correlation between prehospital times and outcomes among severely injured elderly patients.

Weapons of mass destruction preparedness and response for the XIV Pan-American Games, Santo Domingo, 2003.

The Pan-American Games are considered to be the fourth most important international athletic event in the world. Hosted by the city of Santo Domingo, Dominican Republic, the XIV Pan-American Games lasted from 11-17 August 2003. In preparation for the Games, the Security Directorate developed and deployed a Weapons of Mass Destruction (WMD) Unit.

Effectiveness of a simple Internet-based disaster triage educational tool directed toward Latin-American EMS providers.

Background: A previous survey demonstrated a lack of standardization related to disaster triage among Latin-American providers.

Objective: To assess the effectiveness of a short Internet-based educational intervention in disaster and mass-casualty triage. Using three Spanish Internet emergency medical services (EMS) forums, Latin-American providers were invited to participate in the study.

Entomological aspects of Chagas' disease transmission in the domestic habitat, Argentina.

Objective: To study the risk of Trypanosoma cruzi domestic transmission using an entomological index and to explore its relationship with household's characteristics and cultural aspects.

Methods: There were studied 158 households in an endemic area in Argentina. Each household was classified according to an entomological risk indicator (number of risky bites/human).