Objective: To assess the relationship between a marker of epididymal function and both the fragmentation of the sperm nucleus and the integrity and maturity of the sperm membrane in patients with or without varicocele.
Patients And Methods: Semen samples were obtained from men with varicocele grades II and III (n = 60) and from a control group with zoospermia defined as normal (n = 30). Samples were evaluated by a spermiogram, a hypoosmotic swelling test (HOST), neutral α-glucosidase (NAG) enzyme activity, sperm hyaluronan-binding assay (HBA) and DNA fragmentation using a sperm chromatin dispersion (SCD) test.
Male infertility may be due to inflammation or infection of the genital tract among other causes. Male accessory sex glands and sperm function may also be involved in the problem of infertility. This study tries to associate the most frequent bacteria in semen of infertile men including Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum with the seminal characteristics and levels of fructose, citric acid and alpha-neutral glucosidase as markers of the accessory glands.
View Article and Find Full Text PDFIntroduction: Varicocele has been associated with decreased semen quality, not much is known about the effect of varicocele on the accessory sex glands function. The purpose of this study was to evaluate the relationship among varicocele, seminal parameters and biochemical markers of accessory sex glands: neutral alpha glucosidase (NAG, epididymis), fructose (seminal vesicles), prostatic acid phosphatase (PAP) and zinc (prostate).
Materials And Methods: A clinical study was performed in 190 men with varicocele and 100 men normozoospermic as control group.
Varicocele has been associated with decrease in seminal parameters. Selenium (Se), copper (Cu), and zinc (Zn) are trace elements essential for normal spermatogenesis of mammals and play a critical role as antioxidant defense system enzymes. Se, Cu, and Zn are associated with sperm quality in fertile and infertile men.
View Article and Find Full Text PDFAim: To evaluate the effect of presence, grade and anatomical side of varicocele on semen parameters and to identify age-related modifications in semen quality in men with varicocele.
Methods: A prospective clinical study was performed in 363 men with varicocele and 155 normozoospermic men without varicocele. We determined the presence, grade and anatomical localization of varicocele: left (grades I-III), right or bilateral.