Publications by authors named "Giovanny Velasquez"
Clin Lung Cancer
December 2024
Article Synopsis
- Lung cancer is the leading cause of cancer-related deaths globally, but recent advancements in treatment are linked to discoveries from Next Generation Sequencing, particularly the identification of mutations like RBM10.
- A study of 50 patients with NSCLC and RBM10 mutations showed that those with the mutation had a median progression-free survival (PFS) of 6.7 months, significantly lower than the 13.9 months observed in those without the mutation.
- RBM10 mutations were linked to aggressive disease; however, the presence of concurrent mutations such as ZFHX3 and EGFR was associated with a more stable disease state, while mutations like KRAS and TP53 indicated a more aggressive progression.
