Publications by authors named "Giovanni Nunzio Rosano"
Colitis cystica profunda (CCP) is a rare, uncommon and nonneoplastic condition that can occur anywhere in gastrointestinal tract, but its main occurrence is in the rectum and sigmoid colon. It is characterized by the presence of mucin filled cysts, lined by benign epithelium, beneath the muscularis mucosae, usually confined to the submucosa, and it can clinically and radiologically mimic a neoplasm. Here we report a rare case of CCP in a patient with a 2-months history of abdominal pain and severe anemia, associated with diverticulosis.
View Article and Find Full Text PDFArticle Synopsis
- - Solitary fibrous tumor (SFT) is a rare tumor that can occur in various locations in adults, with no gender preference, and can present a wide range of morphological appearances.
- - The study examined 31 cases of SFT from diverse sites, including uncommon areas like the thoracic spine, mesorectal tissue, and breast, highlighting the tumor's versatility in location.
- - Notable morphological characteristics observed in the tumors included lipomatous areas, myxoid changes, and features resembling other tumors, which can lead to diagnostic confusion; thus, pathologists need to be vigilant to distinguish SFTs from other neoplasms.
Triple-negative breast cancer (TNBC) represents about 15% of all breast cancers and is usually characterized by aggressive clinical behavior and a poor prognosis. Four TNBC subgroups have been previously defined with different molecular profiles: (i) luminal androgen receptor (LAR), (ii) mesenchymal (MES), (iii) basal-like immunosuppressed (BLIS) and (iv) basal-like immune-activated (BLIA). Among these, LAR is characterized by the expression of the androgen receptor (AR), and exhibits genomic characteristics that resemble luminal breast cancers, with a still undefined prognosis and clinical behavior.
View Article and Find Full Text PDF