Publications by authors named "Giovanni Mastrantonio di Favero"
Article Synopsis
- This study aimed to evaluate the characteristics of hysterectomy specimens and assess the role of preoperative CA-125 levels and imaging in endometrial cancer patients, ultimately creating a risk matrix for identifying those needing lymphadenectomy.
- A review of 405 patients revealed specific factors—like myometrial infiltration, lymphovascular space involvement, and CA-125 levels—that were used to predict lymph node metastasis, with a developed risk matrix indicating a significant difference in risk based on the presence of these factors.
- The findings suggest that patients without deep invasion or vascular involvement, along with normal CA-125 and imaging results, have a low risk of lymph node involvement, which could help guide decisions on whether to proceed with lymphadenectomy.
Article Synopsis
- The study aimed to assess lymph node status in women with endometrial cancer referred to a Brazilian oncology center, focusing on clinicopathological factors that could suggest the exclusion of lymphadenectomy.
- Researchers analyzed data from 310 women with different types of endometrial cancer, evaluating factors like tumor size, grade, invasion depth, and lymphovascular space invasion to identify correlations with lymph node metastasis.
- Findings indicated that tumor size, myometrial invasion, tumor grade, and lymphovascular space invasion were significantly associated with lymph node involvement, while histological type was not, leading to recommendations for timely hysterectomy and a reevaluation of lymph node dissection needs.
Introduction: The clinical importance of preoperative serum levels of CA 72-4, carcinoembryonic antigen (CEA), CA 19-9, and alpha-fetoprotein (AFP) was prospectively evaluated in 44 patients with gastric cancer.
Method: The serum tumor marker levels were determined by commercial radioimmunoassay kits. Positivity for CA 72-4 (>4 U/mL), CEA (>5 ng/mL), CA 19-9 (>37 U/mL), and AFP (>10 ng/mL) were correlated according to the stage, histology, and lymph node metastasis.