Publications by authors named "Giovanni Francesco Porcheddu"
Article Synopsis
- Epilepsy commonly occurs alongside Alzheimer's disease (AD) and often appears before noticeable memory decline, suggesting a potential link worth studying in early AD stages.
- Research on Tg2576 mice showed that repeated seizures led to memory impairment and increased amyloid-β (Aβ) levels specifically in those with pre-symptomatic AD, indicating a connection between seizures and AD pathology.
- The antiepileptic drug lamotrigine was effective in reversing the neuronal changes and memory deficits caused by seizures, suggesting it could help mitigate the progression of AD in its early stages.
