Organization and Activity of Italian Echocardiographic Laboratories: A Survey of the Italian Society of Echocardiography and Cardiovascular Imaging.

Background: The Italian Society of Echocardiography and Cardiovascular Imaging (SIECVI) conducted a national survey to understand better how different echocardiographic modalities are used and accessed in Italy.

Methods: We analyzed echocardiography laboratory activities over a month (November 2022). Data were retrieved via an electronic survey based on a structured questionnaire, uploaded on the SIECVI website.

Multimodality Imaging for Diagnosis and Characterization of a Cardiac Hydatid Cyst.

Here, we report the case of a young patient admitted to the emergency department because of abdominal pain. Computed tomography revealed a mass within her right heart. Through serial multimodality imaging testing, including computed tomography, three-dimensional (2D)- and three-dimensional echocardiography, as well as cardiac magnetic resonance, the diagnosis of cardiac involvement in the course of infection was hypothesized.

Cultivar-Dependent Anticancer and Antibacterial Properties of Silver Nanoparticles Synthesized Using Leaves of Different Trees.

The green synthesis of nanoparticles (NPs) is currently under worldwide investigation as an eco-friendly alternative to traditional routes (NPs): the absence of toxic solvents and catalysts make it suitable in the design of promising nanomaterials for nanomedicine applications. In this work, we used the extracts collected from leaves of two cultivars ( and ) belonging to the species , to synthesize silver NPs (AgNPs) in different pH conditions and low temperature. NPs underwent full morphological characterization with the aim to define a suitable protocol to obtain a monodispersed population of AgNPs.

Is Left Ventricular Noncompaction Only a Morphological Feature? A Case of Disappearance of Noncompaction after Surgical Correction of Aorto-Right Ventricular Fistula, Interventricular Septal Defect and Aortic Stenosis.

A 55-year-old man complaining of worsening dyspnea on exertion was diagnosed with restrictive interventricular septal defect, left ventricular noncompaction (LVNC), mild aortic valve stenosis and aorto-right ventricular fistula. He underwent surgical aortic valve replacement with a mechanical bileaflet valve (St. Jude n.

Investigating the relation between stochastic differentiation, homeostasis and clonal expansion in intestinal crypts via multiscale modeling.

Colorectal tumors originate and develop within intestinal crypts. Even though some of the essential phenomena that characterize crypt structure and dynamics have been effectively described in the past, the relation between the differentiation process and the overall crypt homeostasis is still only partially understood. We here investigate this relation and other important biological phenomena by introducing a novel multiscale model that combines a morphological description of the crypt with a gene regulation model: the emergent dynamical behavior of the underlying gene regulatory network drives cell growth and differentiation processes, linking the two distinct spatio-temporal levels.

Early systemic sclerosis: analysis of the disease course in patients with marker autoantibody and/or capillaroscopic positivity.

Objective: To investigate whether patients affected by 1 of the 3 subsets of early systemic sclerosis (SSc; scleroderma), i.e., subset I, Raynaud's phenomenon with SSc marker autoantibodies and typical capillaroscopic findings; subset II, autoantibody positive only; and subset III, capillaroscopy positive only and not satisfying the 2013 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for SSc at admission, differ from each other in the time to satisfy the criteria.

Calamitic and antinematic orientational order produced by the generalized Straley lattice model.

We consider here a classical model, consisting of D_{2h}-symmetric particles in a three-dimensional simple-cubic lattice; the pair potential is isotropic in orientation space, and restricted to nearest neighbors. The simplest potential model is written in terms of the squares of the scalar products between unit vectors describing the three interacting arms of the molecules, as proposed in previous literature. Two predominant antinematic couplings of equal strength (+1) are perturbed by a comparatively weaker calamitic one, parameterized by a coupling constant -z ranging in [-1,0].

Early systemic sclerosis: marker autoantibodies and videocapillaroscopy patterns are each associated with distinct clinical, functional and cellular activation markers.

Introduction: Early systemic sclerosis (SSc) is characterized by Raynaud's phenomenon together with scleroderma marker autoantibodies and/or a scleroderma pattern at capillaroscopy and no other distinctive feature of SSc. Patients presenting with marker autoantibodies plus a capillaroscopic scleroderma pattern seem to evolve into definite SSc more frequently than patients with either feature. Whether early SSc patients with only marker autoantibodies or capillaroscopic positivity differ in any aspect at presentation is unclear.

Antinematic orientational order produced by an extreme case of the generalized Straley lattice model.

We address here a special, extreme case of the quadratic pair interaction potential between classical, D(2h)-symmetric particles (the generalized Straley model) on a three-dimensional simple cubic lattice. The model involves predominant antinematic couplings and it has been studied by Monte Carlo simulation and a molecular field treatment. The obtained results show a second-order transition between the isotropic phase and the low-temperature one, exhibiting uniaxial antinematic order.

A review of spatial computational models for multi-cellular systems, with regard to intestinal crypts and colorectal cancer development.

Colon rectal cancers (CRC) are the result of sequences of mutations which lead the intestinal tissue to develop in a carcinoma following a "progression" of observable phenotypes. The actual modeling and simulation of the key biological structures involved in this process is of interest to biologists and physicians and, at the same time, it poses significant challenges from the mathematics and computer science viewpoints. In this report we give an overview of some mathematical models for cell sorting (a basic phenomenon that underlies several dynamical processes in an organism), intestinal crypt dynamics and related problems and open questions.

Orientationally ordered phase produced by fully antinematic interactions: a simulation study.

We consider here a classical model, consisting of D(2h) symmetric particles, whose centers of mass are associated with a three-dimensional simple-cubic lattice; the pair potential is isotropic in orientation space, and restricted to nearest neighbors. Two orthonormal triads define orientations of a pair of interacting particles; the simplest potential models proposed in the literature can be written as a linear combination involving the squares of the scalar products between corresponding unit vectors only, thus depending on three parameters, and making the interaction model rather versatile. A coupling constant with negative sign tends to keep the two interacting unit vectors parallel to each other, whereas a positive sign tends to keep them mutually orthogonal (antinematic coupling).

Director libration in nematoacoustics.

We extended the analysis of a variational theory for nematoacoustics recently proposed by Virga [Phys. Rev. E 80, 031705 (2009)] by allowing the nematic director to vibrate about an average orientation at the frequency of a propagating wave, a periodic motion that we call the director libration.

Time spent for activation of non-profit studies in oncology in Italy.

Aim: The aim of this paper is to describe the time spent to activate oncological non-profit clinical trials promoted in Italy by the National Cancer Institute of Naples, following the implementation of recent European laws.

Methodology: Data about the process of activation of 5 non-profit multicentre clinical trials were prospectively collected through a web-based system. The impact of European guidelines was assessed by comparing the efficiency of the process between applications started before and after the decree introducing in Italy the Clinical Trial Application form (MD-CTA).

Mesogenic lattice models with partly antinematic interactions producing uniaxial nematic phases.

The present paper considers nematogenic lattice models, involving particles of D_{2h} symmetry, whose centers of mass are associated with a three-dimensional simple cubic lattice; the pair potential is isotropic in orientation space and restricted to nearest neighbors. Let two orthonormal triads define orientations of a pair of interacting particles; the simplest potential models proposed in the literature can be reduced to a linear combination involving the squares of the scalar products between corresponding unit vectors only and depending on three parameters. By now, various sets of potential parameters have been proposed and studied in the literature, some of which capable of producing biaxial orientational order at sufficiently low temperature.

Biaxial and uniaxial phases produced by partly repulsive mesogenic models involving D2h molecular symmetries.

The present paper considers biaxial nematogenic lattice models, involving particles of D2h symmetry, whose centers of mass are associated with a three-dimensional simple-cubic lattice. The pair potential is isotropic in orientation space and restricted to nearest neighbors. Let two orthonormal triads define orientations of a pair of interacting particles.

[An atypical case of tako-tsubo syndrome presenting with symptomatic bradycardia].

The tako-tsubo syndrome (transient left ventricular apical ballooning with normal coronary arteries), initially described in Japanese patients, is now being increasingly observed worldwide and should be considered in the differential diagnosis of acute coronary syndromes. Angina-like chest pain, electrocardiographic changes and an increase in myocardial markers are often present, as well as history of acute stressful events preceding symptom onset. We report the case of an Asiatic woman in whom typical, reversible abnormalities in left ventricular motion were associated with symptomatic junctional bradycardia.

Universal mean-field phase diagram for biaxial nematics obtained from a minimax principle.

We study a class of quadratic Hamiltonians which describe both fully attractive and partly repulsive molecular interactions, characteristic of biaxial liquid crystal molecules. To treat the partly repulsive interactions we establish a minimax principle for the associated mean-field free energy. We show that the phase diagram described by Sonnet [Phys.

Bifurcation analysis and computer simulation of biaxial liquid crystals.

We extend the analysis of a mean-field model for biaxial liquid crystals recently proposed by Sonnet et al. [Phys. Rev.

Tricritical points in biaxial liquid crystal phases.

We further pursue the analysis of a mean-field model recently proposed by Sonnet [Phys. Rev. E 67, 061701 (2003)] to describe nematic biaxial phases.

Analysis of valve motion after the reimplantation type of valve-sparing procedure (David I) with a new aortic root conduit.

Background: The reimplantation type of valve-sparing procedure does not allow proper reconstruction of the sinuses of Valsalva. We assessed the valve motion after a reimplantation type (David I) of valve-sparing procedure using a new Dacron conduit that incorporates sinuses of Valsalva.

Methods: Nine consecutive patients undergoing an aortic valve-sparing procedure using the new conduit were studied using two-dimensional transesophageal echocardiography shortly (2 +/- 1 months) after operation to determine root distensibility, expressed as percent change in radius and as pressure strain of the elastic modulus.

One-year appraisal of a new aortic root conduit with sinuses of Valsalva.

Objectives: We evaluate the clinical results 1 year after an anatomic reconstruction of the aortic root in which we used a specifically designed aortic root prosthesis that incorporates the sinuses of Valsalva.

Material And Methods: The new aortic Dacron prosthesis has a proximal portion in the Dacron conduit that expands on implantation, creating pseudosinuses. During a 12-month period, 28 patients (mean age 59 +/- 14 years) underwent a Bentall operation (12 cases), a remodeling procedure (7 cases), and a reimplantation procedure (9 cases) with the use of a new aortic root conduit.