Publications by authors named "Giovanni Battista Vadacca"
Article Synopsis
- The study investigates the relationship between iron metabolism and inflammation in 32 adult COVID-19 patients admitted for acute respiratory failure in Italy.
- Patients were divided into three groups based on their oxygen levels, revealing significant differences in white blood cell counts, iron levels, and inflammatory markers across these groups.
- Despite limitations, the findings emphasize the importance of iron dysregulation and inflammation in the severity of COVID-19 and its impact on tissue and organ damage.
Coronavirus disease (COVID-19) is a systemic disease which can cause multiple organ failure and death primarly due to vascular endothelium injury. Severe acute respiratory distress syndrome (ARDS) is the main cause of death: its management and treatment should be tailored to the individual COVID-19 patient's phenotype. Early diagnosis of COVID-19 is paramount for disease treatment and infection control.
View Article and Find Full Text PDFObjective: The dramatic worldwide CoVID-19 infection requires the identification of a reliable and inexpensive tool to quickly discriminate patients with a more unfavorable outcome.
Methods: We performed routine laboratory tests suitable to identify tissue damage and inflammatory status in 123 consecutive CoVID-19 patients admitted to the Emergency Department of the hospital of Piacenza (Emilia-Romagna, Northern Italy). The results were correlated with patients' respiratory function evaluated by the partial pressure of arterial oxygen to fraction of inspired oxygen ratio (PaO2/FiO2).