Publications by authors named "Giovanni Alessi"

Background:  During resection of intrinsic brain tumors in eloquent areas, particularly under awake mapping, subcortical stimulation is mandatory to avoid irreversible deficits by damaging white fiber tracts. The current practice is to alternate between subcortical stimulation with an appropriate probe and resection of tumoral tissue with an ultrasound aspiration device. Switching between different devices induces supplementary movement and possible tissue trauma, loss of time, and inaccuracies in the localization of the involved area.

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Article Synopsis
  • The study aimed to evaluate the effectiveness of the DIAM spinal stabilization system in reducing back pain, disability, and improving patient quality of life over 24 months, comparing it to standard herniectomy treatment.
  • Out of 165 patients, 146 with single-level disc herniation were randomized into two groups: one received the DIAM system along with surgery, while the other underwent surgery alone; both groups showed significant improvements in pain and disability, but no major differences between them were found.
  • Despite a higher percentage of patients in the DIAM group achieving minimal clinical importance in back pain relief, overall outcomes and complication rates were similar for both treatments, indicating equivalent efficacy and safety.
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Case Report: Two patients with a posterior fossa arachnoid cyst responsible for isolated facial nerve palsy are reported.

Discussion: The relationships between the cyst and the facial nerve and between the facial nerve palsy and the size variation of the cyst are discussed and documented by pre- and postoperative magnetic resonance imaging.

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Tuberculous involvement of the spinal subdural and intramedullary compartments is extremely uncommon. Simultaneous involvement of both compartments has never been reported, to our knowledge. We present an HIV-positive patient with such kind of combined involvement.

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Objective And Importance: We report two patients with benign uterine leiomyoma metastasizing to the nervous system, respectively, to the skull base and to the spine. Although primary cranial and metastatic spinal leiomyomas have been rarely described, to our knowledge no case of benign leiomyoma metastasizing to the skull base has been reported before.

Clinical Presentation: Two female patients with history of hysterectomy for benign leiomyoma, subsequently metastasizing to the lungs and smooth muscles of the skin, presented with a focal neurologic deficit.

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Hemilingual spasm is a little-known movement disorder, presenting as intermittent paroxysmal involuntary contractions of half of the tongue muscles. The authors report a case of hemilingual spasm caused by an arachnoid cyst. After marsupialization of the cyst, the patient's symptoms immediately resolved.

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