ThyroidPrint®: clinical utility for indeterminate thyroid cytology.

Molecular testing contributes to improving the diagnosis of indeterminate thyroid nodules (ITNs). ThyroidPrint® is a ten-gene classifier aimed to rule out malignancy in ITN. Post-validation studies are necessary to determine the real-world clinical benefit of ThyroidPrint® in patients with ITN.

A Thyroid Genetic Classifier Correctly Predicts Benign Nodules with Indeterminate Cytology: Two Independent, Multicenter, Prospective Validation Trials.

Although most thyroid nodules with indeterminate cytology are benign, in most of the world, surgery remains as the most frequent diagnostic approach. We have previously reported a 10-gene thyroid genetic classifier, which accurately predicts benign thyroid nodules. The assay is a prototype diagnostic kit suitable for reference laboratory testing and could potentially avoid unnecessary diagnostic surgery in patients with indeterminate thyroid cytology.

A 10-Gene Classifier for Indeterminate Thyroid Nodules: Development and Multicenter Accuracy Study.

Background: In most of the world, diagnostic surgery remains the most frequent approach for indeterminate thyroid cytology. Although several molecular tests are available for testing in centralized commercial laboratories in the United States, there are no available kits for local laboratory testing. The aim of this study was to develop a prototype in vitro diagnostic (IVD) gene classifier for the further characterization of nodules with an indeterminate thyroid cytology.

Salt stress response triggers activation of the jasmonate signaling pathway leading to inhibition of cell elongation in Arabidopsis primary root.

Salinity is a severe abiotic stress that affects irrigated croplands. Jasmonate (JA) is an essential hormone involved in plant defense against herbivory and in responses to abiotic stress. However, the relationship between the salt stress response and the JA pathway in Arabidopsis thaliana is not well understood at molecular and cellular levels.

High throughput selection of novel plant growth regulators: Assessing the translatability of small bioactive molecules from Arabidopsis to crops.

Plant growth regulators (PGRs) have become an integral part of agricultural and horticultural practices. Accordingly, there is an increased demand for new and cost-effective products. Nevertheless, the market is limited by insufficient innovation.

How the new web generations are changing library and information services.

The new Web generations are influencing the minds and changing the habits of software developers and end users. Users, librarians, and information services professionals can interact more efficiently, creating additional information and content and generating knowledge. This new scenario is also changing the behavior of information providers and users in health sciences libraries.

Improving health communication. Supporting the practice of health communication.

Background: Health authorities, hospitals, commercial enterprises, and mass media all deliver health and medical communication in different forms. With such a vast amount of biomedical and clinical information available, any action to ensure the spread of clinically relevant news items is welcome.

Objectives: This paper tries to define a new role for health science librarians in improving medical communication and reporting.

Information sources in biomedical science and medical journalism: methodological approaches and assessment.

Throughout the world the public is showing increasing interest in medical and scientific subjects and journalists largely spread this information, with an important impact on knowledge and health. Clearly, therefore, the relationship between the journalist and his sources is delicate: freedom and independence of information depend on the independence and truthfulness of the sources. The new "precision journalism" holds that scientific methods should be applied to journalism, so authoritative sources are a common need for journalists and scientists.