Publications by authors named "Giovanna Colombo"
Article Synopsis
- Thrombotic complications are a major cause of early graft failure in pediatric liver transplantation, and there's no standardized prevention method.
- A study analyzed the impact of early intravenous unfractionated heparin on reducing thrombotic complications in children undergoing liver transplants by comparing patient outcomes before and after implementing heparin treatment.
- Results showed that patients receiving heparin had a significantly lower incidence of venous thrombosis (2.5%) compared to those who did not (7.9%), suggesting that heparin can effectively prevent this complication without increasing bleeding risks, but further research is needed for confirmation.
Background In patients with acute ischemic stroke and atrial fibrillation, early anticoagulation prevents ischemic recurrence but with the risk of hemorrhagic transformation ( HT ). The aims of this study were to evaluate in consecutive patients with acute stroke and atrial fibrillation (1) the incidence of early HT, (2) the time to initiation of anticoagulation in patients with HT , (3) the association of HT with ischemic recurrences, and (4) the association of HT with clinical outcome at 90 days. Methods and Results HT was diagnosed by a second brain computed tomographic scan performed 24 to 72 hours after stroke onset.
View Article and Find Full Text PDFAim: To review current literature of thrombosis prophylaxis in pediatric liver transplantation (PLT) as thrombosis remains a critical complication.
Methods: Studies were identified by electronic search of MEDLINE, EMBASE and Cochrane Library (CENTRAL) databases until March 2018. The search was supplemented by manually reviewing the references of included studies and the references of the main published systematic reviews on thrombosis and PLT.
Early Recurrence and Major Bleeding in Patients With Acute Ischemic Stroke and Atrial Fibrillation Treated With Non-Vitamin-K Oral Anticoagulants (RAF-NOACs) Study.
J Am Heart Assoc
November 2017
Article Synopsis
- The study investigates the optimal timing for administering non-vitamin K oral anticoagulants (NOACs) in patients with acute ischemic stroke and atrial fibrillation, focusing on early recurrence of stroke and major bleeding within 90 days post-treatment.
- A total of 1,127 patients participated, with diverse treatment groups receiving dabigatran, rivaroxaban, or apixaban; results revealed a low incidence of early recurrence (2.8%) and major bleeding (2.4%).
- Patients starting NOACs within 2 days of stroke had higher rates of complications (12.4% composite rate), compared to delayed initiation (3-14 days had 2.1%, and >14 days
Background And Purposes: This study was designed to derive and validate a score to predict early ischemic events and major bleedings after an acute ischemic stroke in patients with atrial fibrillation.
Methods: The derivation cohort consisted of 854 patients with acute ischemic stroke and atrial fibrillation included in prospective series between January 2012 and March 2014. Older age (hazard ratio 1.
Sleep is a very important element for the development of a premature newborn, because it helps in creating good clinical condition, good weight gain, mastering full oral feeding and improving parent-infant relationship as well. Moreover, the development of a correct sleeping-awaking pattern is a key factor for the development of the brain. To protect sleep is important to modify the environment, for example, reducing noise levels, creating period of semi darkness and protecting infant face from direct light.
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