Publications by authors named "Giovana Castelli"
Article Synopsis
- Heart rate variability (HRV) is an important indicator of cardiovascular health and is generally lower in people living with HIV (PLWH).
- This study examined the impact of a short-term aerobic training program on HRV and endothelial function in this group.
- After completing 24 sessions of aerobic training, participants showed significant improvements in several HRV measures, indicating that short-term exercise can benefit heart health for men living with HIV.
Background: Massively obese subjects frequently undergo pulmonary function tests nowadays. Obesity-associated decreases in key operating lung volumes (reduced inspiratory capacity and reduced vital capacity) are particularly concerning because they may shorten the "room" for tidal volume expansion with negative physiologic and sensory consequences.
Research Question: Is massive obesity associated with reduced operating lung volumes? If so, is this effect more pronounced in men than women?
Study Design And Methods: We performed an observational, retrospective study in a tertiary, hospital-based laboratory.
Article Synopsis
- FVC may underestimate slow vital capacity (SVC) due to early airway closure at low lung volumes, raising questions about the use of SVC in spirometry for detecting airflow issues.
- A study of 13,893 adult outpatients found that 20.4% showed discordance (normal FEV/FVC but low FEV/SVC), which was linked to worse lung function and higher resistance, particularly in younger, obese individuals.
- Replacing FVC with SVC in the FEV/VC ratio can help identify mild airflow obstruction in younger and obese subjects, but may lead to false-positive findings in elderly patients, suggesting caution in this group.