Publications by authors named "Giorgio Stortini"
Article Synopsis
- Nicotinamide phosphoribosyltransferase (NAMPT) plays a crucial role in recycling nicotinamide to keep NAD levels stable in cells and is seen as a potential target for cancer and inflammatory disease treatments.
- A new class of NAMPT inhibitors has been developed, with the compound 30c showing strong activity in both tumor models and significantly improving colitis in mice.
- This research suggests that NAMPT inhibitors could not only be effective against tumors but may also have new therapeutic applications, like treating inflammatory conditions.
