Publications by authors named "Giorgio Spiniello"

Article Synopsis
  • Very high-power short-duration (vHPSD) radiofrequency ablation for pulmonary vein isolation shows reduced ablation times and better patient tolerance compared to traditional methods.
  • In a study of 58 patients undergoing vHPSD, results indicated significantly shorter procedural and RF times, along with reduced need for anesthetic drugs compared to a control group.
  • The vHPSD method allowed for effective PV isolation under mild conscious sedation, with a notably lower pain experience reported by patients.
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Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.

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Article Synopsis
  • The case discusses a patient who experienced recurrent intra-atrial reentrant tachycardia following surgery for a sinus venosus atrial septal defect.
  • The episodes were resistant to medication, significantly affecting the patient’s quality of life.
  • To address this, a specialized electrophysiology study was conducted using 3D mapping, leading to successful treatment with radiofrequency ablation, which shows promise for similar postoperative arrhythmias in repaired congenital heart disease patients.
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As of January 2020, a new pandemic has spread from Wuhan and caused thousands of deaths worldwide. Several studies have observed a relationship between coronavirus disease (COVID-19) infection and the cardiovascular system with the appearance of myocardial damage, myocarditis, pericarditis, heart failure and various arrhythmic manifestations, as well as an increase in thromboembolic risk. Cardiovascular manifestations have been highlighted especially in older and more fragile patients and in those with multiple cardiovascular risk factors such as cancer, diabetes, obesity and hypertension.

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The actual Coronavirus Disease (COVID 19) pandemic is due to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a member of the coronavirus family. Besides the respiratory involvement, COVID 19 patients frequently develop a pro-coagulative state caused by virus-induced endothelial dysfunction, cytokine storm and complement cascade hyperactivation. It is common to observe diffuse microvascular thrombi in multiple organs, mostly in pulmonary microvessels.

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