Handedness in Alzheimer Disease: A Systematic Review.

Handedness has been a topic of scientific interest for many years. However, false and misleading ideas have dominated this field with a still limited amount of research into the association with clinical disorders like Alzheimer disease (AD). In accordance with PRISMA guidelines, PubMed, Embase, and Cochrane Library were searched for studies regarding the association of handedness and AD.

Neurological Examination: An Evaluation of Video-Based Learning.

Objective This study aimed to systematically review and assess educational YouTube videos on neurological examination. Methods YouTube was screened for educational videos on neurological examination. A scoring system (involving five major and six minor criteria) was used to assess videos.

Evaluation of Cell-Specific Alterations in Alzheimer's Disease and Relevance of In Vitro Models.

Alzheimer's disease (AD) is a neurodegenerative disorder classically characterized by two neuropathological hallmarks: β-amyloid plaques and tau tangles in the brain. However, the cellular and molecular mechanisms involved in AD are still elusive, which dampens the possibility of finding new and more effective therapeutic interventions. Current in vitro models are limited in modelling the complexity of AD pathogenesis.

Sex and age dimorphism of the gut-brain axis in ischemic stroke: A systematic review of preliminary studies.

Recent studies have shown that stroke risk and outcomes are influenced by the microbiota composition and its strict relationship with the immune system. Age and sex are the main non-modifiable factors that shape microbiome composition. In order to evaluate the effects of these two variables on the microbiome in stroke pathogenesis we performed a systematic review of literature, including 10 studies in the final selection.

Gut permeability and osteoarthritis, towards a mechanistic understanding of the pathogenesis: a systematic review.

Osteoarthritis (OA) is the most common condition affecting human joints. Along with mechanical and genetic factors, low-grade inflammation is increasingly supported as a causal factor in the development of OA. Gut microbiota and intestinal permeability, the disruption of tight junction competency, are proposed to explain a gut-joint axis through the interaction with the host immune system.