Publications by authors named "Giorgio Cucchi"

The 2013/59/Euratom Directive reduced the occupational exposure limits for the lens. Since it has become crucial to estimate the dose absorbed by the lens, we have studied the individual variability of exposed workers' ocular conformations with respect to the data estimated from their personal dosimetry. The anterior eye conformations of 45 exposed workers were acquired using Scheimpflug imaging and classified according to their sight conditions (emmetropia, myopia or hypermetropia).

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The current framework of radiological protection of occupational exposed medical workers reduced the eye-lens equivalent dose limit from 150 to 20 mSv per year requiring an accurate dosimetric evaluation and an increase understanding of radiation induced effects on Lens cells considering the typical scenario of occupational exposed medical operators. Indeed, it is widely accepted that genomic damage of Lens epithelial cells (LEC) is a key mechanism of cataractogenesis. However, the relationship between apoptosis and cataractogenesis is still controversial.

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Article Synopsis
  • Radiation therapy is commonly used to treat tumors, but challenges like recurrence and radioresistance limit survival rates for some cancer patients.
  • The study investigates the effects of very high dose rate radiation using a special pulsed plasma device on two radioresistant melanoma cell lines, SK-Mel28 and A375.
  • Results indicate that this new method is more effective in damaging melanoma cells compared to traditional X-ray treatments, suggesting potential for improved clinical outcomes in the future.
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