Publications by authors named "Giorgio A Baretta"

Background: Endoscopic approaches exist for targeting weight regain after Roux-en-Y gastric bypass (RYGB), including endoscopic suturing, clipping, and sclerotherapy. Argon plasma coagulation (APC) is a noncontact electrocoagulation method, and when used in RYGB patients, it has shown reduction in the diameter of the gastrojejunal anastomosis.

Objectives: To study the effectiveness of APC for weight regain in terms of weight loss for RYGB patients, from eight bariatric centers.

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Background: The bariatric surgery may cause some nutritional deficiencies.

Aim: To compare the serum levels of biochemical markers, in iimmediate post-surgical patients who were submitted to bariatric surgery.

Methods: Non-concurrent prospective cross-sectional study.

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Background And Objectives: The introduction of propofol (2,6-diisopropylphenol) as a sedative agent has transformed the area of sedation for endoscopic procedures. However, a major drawback of sedation with the use of propofol is its high incidence of injection pain. The most widely used technique in reducing propofol injection pain is through the association of other drugs.

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Background: Bariatric surgery, especially Roux-en-Y gastric bypass, can cause serious nutritional complications arising from poor absorption of essential nutrients. Secondary hyperparathyroidism is one such complications that leads to increased parathyroid hormone levels due to a decrease in calcium and vitamin D, which may compromise bone health.

Aim: To compare calcium carbonate and calcium citrate in the treatment of secondary hyperparathyroidism.

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Background And Objectives: The introduction of propofol (2,6-diisopropylphenol) as a sedative agent has transformed the area of sedation for endoscopic procedures. However, a major drawback of sedation with the use of propofol is its high incidence of injection pain. The most widely used technique in reducing propofol injection pain is through the association of other drugs.

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Background: Bariatric surgery is effective treatment for weight loss, but demand continuous nutritional care and physical activity. They regain weight happens with inadequate diets, physical inactivity and high alcohol consumption.

Aim: To investigate in patients undergoing Roux-Y-of gastroplasty weight regain, nutritional deficiencies, candidates for the treatment with endoscopic argon plasma, the diameter of the gastrojejunostomy and the size of the gastric pouch at the time of treatment with plasma.

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Purpose: To evaluate the influence of the cyclosporine in liver regeneration in rats submitted to an experimental model of 70% hepatectomy.

Methods: Forty male rats were randomly divided in four subgroups (C.24h, C.

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Background: Bariatric surgery, especially Roux-en-Y gastric bypass is an effective treatment for refractory morbid obesity, causing the loss of 75% of initial excess weight. After the surgery, however, weight regain can occur in 10-20% of cases. To help, endoscopic argon plasma coagulation (APC) is used to reduce the anastomotic diameter.

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Objective: To evaluate the influence of sirolimus on liver regeneration triggered by resection of 70% of the liver of adult rats.

Methods: we used 40 Wistar rats randomly divided into two groups (study and control), each group was divided into two equal subgroups according to the day of death (24 hours and seven days). Sirolimus was administered at a dose of 1mg/kg in the study group and the control group was given 1 ml of saline.

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Background: The failure of approximately 20 % of obese patients who undergo Roux-en-Y gastric bypass (RYGB) to maintain weight loss over the following 18-24 months is related to the surgical procedure, to the patient, or both. Although the underlying mechanisms are uncertain, one factor that has been postulated is the dilation of the gastrojejunal anastomosis. The objective was to evaluate the safety and efficacy of the serial use of argon plasma coagulation (APC) in reducing the diameter of the dilated gastrojejunal anastomosis and post-RYGB weight regain.

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Objective: To analyze, during two different moments of liver regeneration, the effect of the immunosuppressant Tacrolimus on the 70% hepatectomy model-induced liver regeneration in adult rats.

Methods: Forty Wistar adult rats, weighing 510.08 + 11.

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Objective: To compare safety and efficacy of propofol with midazolam for deep sedation in the colonoscopy.

Methods: In a prospective way, 66 patients underwent colonoscopy--50 patients received propofol in an average dose of 3,25 mgxkg-1 and 16 patients (control group) received midazolam with total average dose of 2,05 mgxkg-1. The dose of medication was titrated according to patient need.

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Article Synopsis
  • The study aimed to identify factors that predict treatment failure in adult patients with blunt splenic injuries managed non-surgically.
  • NST failure occurred in 19.6% of patients, primarily due to abdominal pain, hemodynamic instability, and other complications, with higher failure rates associated with more severe injury grades.
  • Key findings indicated that patients with lower Injury Severity Scores (ISS) had a lower failure rate, while those with higher ISS showed a significantly increased risk, suggesting that injury severity is a key prognostic factor.
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Article Synopsis
  • The study aimed to determine the best power setting (50W vs. 70W) for argon plasma thermocoagulation in treating Barrett's esophagus (BE) while minimizing symptoms.
  • In a sample of 15 patients (average age 53), those treated at 70W showed a trend toward less specialized columnar metaplasia and a more effective ablation compared to those treated at 50W.
  • Pain was the main symptom experienced post-procedure, lasting an average of 10 days, but there were no significant differences in symptom severity or mucosal penetration between the two power settings.
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Background: Wound contractures can cause severe deformities and disabilities. Recent studies have suggested that leukotriene receptor antagonists have an inhibitory effect on the healing contraction process. This study aimed to evaluate the influence of the leukotriene inhibitor montelukast on the cutaneous healing process and the wound contraction phenomenon in rats.

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Background: Intra-abdominal infections are common and are associated with elevated morbidity and mortality. The microorganisms that cause intra-abdominal infections are usually from the gastrointestinal flora, mainly E. coli and Bacteroides fragilis.

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Background: [corrected] Hepatocellular carcinoma is the most frequent malignant hepatic tumor in humans, and its association with cirrhosis makes the therapeutic approach still a challenge. Liver transplantation is the treatment of choice for cirrhotic patients with unresectable early hepatocellular carcinoma

Aim: To evaluate the post-transplant outcome of a cohort of 15 cirrhotic patients with preoperative diagnosis of unresectable early hepatocellular carcinoma according the Milan criteria who underwent liver transplantation between September 1991 and December 2003

Methods: We retrospectively reviewed the clinical data from 15 liver transplant recipients and the explanted livers were assessed for the efficacy of preoperative therapy. Patient survival and tumor recurrence were evaluated as primary outcome measures

Results: The mean age of the patients was 49.

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Background: Quality of life of the donor after living donor liver transplantation has not been evaluated in Brazil yet.

Aim: To evaluate the quality of live of the donor after living donor liver transplantation.

Methods: Of a total of 300 liver transplantations, 51 were of living donors.

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