Publications by authors named "Giorgina B Piccoli"

Background: Hemodialysis (HD) contributes significantly to healthcare's carbon footprint. Worldwide about 100,000 dialysis machines end their life cycle each year. Our aim was to analyze the composition and the potential for recyclability of two dialysis machines, from the two companies with the largest market share, which had met their end-of-use terms (10-12 years of use according to French regulations).

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  • * Historical famines, particularly the Dutch Hunger Winter and the Great Chinese Famine, provide critical insights into the impacts of prenatal starvation on health across generations.
  • * There is some disagreement among studies about the specific risks and timing of starvation during pregnancy, and gender differences further complicate the understanding of these effects.
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  • A 29-year-old pregnant woman from Equatorial Guinea experienced severe malaria due to Plasmodium falciparum, leading to complications such as cerebral malaria and acute kidney injury (AKI), necessitating renal replacement therapy and a kidney biopsy.
  • During her hospitalization, various tests confirmed her malaria diagnosis, and she was treated with antimalarial medications while experiencing significant symptoms including hypotension and haematological issues.
  • The kidney biopsy revealed active tubulointerstitial nephritis, and after intensive dialysis, her kidney function improved, allowing for a successful cesarean delivery and subsequent recovery without deterioration in kidney health.*
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Preeclampsia and hypertensive disorders of pregnancy complicate 3 to 5% of all pregnancies. Chronic kidney disease (CKD), at any stage, reportedly affects 3% of women in childbearing age but most of the time is underdiagnosed, especially in asymptomatic early stages. The link between preeclampsia/hypertensive disorders of pregnancy and CKD is bidirectional and women experiencing a preeclampsia/hypertensive disorder of pregnancy episode are at higher risk for developing CKD later in life, as well as metabolic and cardiovascular diseases.

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Contraception, pregnancy and fertility are seldom discussed with women receiving dialysis and the medical staff of dialysis centres. Since the majority of women on dialysis are past childbearing age, these themes are not always given proper consideration and this category of patients may be missing important information. Young women of childbearing age who are on dialysis frequently experience sexual dysfunction and hormonal disorders of the hypothalamic-pituitary-gonadal axis.

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Chronic kidney disease (CKD) is linked to an elevated risk of malnutrition and sarcopenia, contributing to the intricate network of CKD-related metabolic disorders. Adipokines and myokines are markers and effectors of sarcopenia and nutritional status. The aim of this study was to assess whether the adipokine-myokine signature in patients on kidney replacement therapy could help identify malnutrition and sarcopenia.

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The ongoing climate change and the ecological challenges call for sustainable medicine and, in our field, sustainable kidney care. Dialysis is life-saving and resource-consuming, and high water consumption is one of the main concerns. Circular water economy, meaning reuse and recycling of water, and recovering resources can help reducing emissions and enhancing resilience to climate change.

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Pregnancy in women living with chronic kidney disease (CKD) was often discouraged due to the risk of adverse maternal-fetal outcomes and the progression of kidney disease. This negative attitude has changed in recent years, with greater emphasis on patient empowerment than on the imperative 'non nocere'. Although risks persist, pregnancy outcomes even in advanced CKD have significantly improved, for both the mother and the newborn.

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