Facial Aging Improvement Case Study Using a Novel Combination of Retinol, Niacinamide, and Terminalia Chebula.

For decades, retinoids have been considered the gold standard of treatment for a variety of skin conditions.1,2 As the bioavailable form of vitamin A, retinoic acid has demonstrated the ability to reduce skin discoloration, stimulate collagen production, reduce rhytids, improve acne, and uneven skin texture.3,4 Retinoic acid is a potent drug with high bioavailability.

Peptide-pro complex serum: Investigating effects on aged skin.

Background: Effective anti-aging treatments are an unmet consumer need.

Aim: Ex vivoand clinical tests have evaluated the efficacy of a topical facial serum containing a proprietary blend of neuropeptides, proteins, amino acids, and marine extracts on aged skin.

Methods: In the ex vivo study the facial serum was compared to a commercially marketed face serum and to an untreated control on skin explants using microrelief, smoothness, and epidermal thickness endpoints.

Amino acid complex (AAComplex) benefits in cosmetic products: In vitro and in vivo clinical studies.

Background: Amino acids are major components of skin's natural moisturizing factors and play a role in regulating skin hydration and skin pH.

Objective: This research examines a proprietary amino acid complex technology (AAComplex) designed to help reduce skin irritation and repair skin damage.

Methods: In- vitro Scratch Assay HaCaT cells are scratched, and the wounds are imaged at different time points until the closure of the scratch wound is detected.