Publications by authors named "Giorgia Presicce"

Article Synopsis
  • The text discusses the ethical and legal considerations surrounding the collection of biological samples and data for research, especially in the context of neurological diseases and the role of biobanking.
  • A study evaluated attitudes towards donating samples for biobanks among 1,454 participants, including healthy volunteers and patients with neurological conditions, with a high level of agreement on participation in biobanking.
  • Key findings show significant differences in preferences regarding the return of results and data sharing, notably that healthy volunteers were more likely to want to remain uninformed about results compared to patients.
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Article Synopsis
  • The management of multiple sclerosis (MS) has grown increasingly complex, necessitating a multidisciplinary team that includes infectious disease specialists to address potential infection risks associated with the disease and disease-modifying treatments (DMTs).
  • From 2015 to 2019, a study at an MS center revealed that out of 1088 patients, 107 received infectious disease consultations, with a noted increase in consultations each year, especially when starting treatment.
  • The findings indicate a rise in awareness regarding infectious complications in MS patients, highlighting the importance of collaboration between neurologists and infectious disease experts to prioritize prevention strategies like vaccinations and prophylactic treatments.
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Recent studies estimated an incidence of 4-25% of disease rebound after withdrawal of fingolimod (FTY) for any reason, but specific data on disease reactivation after FTY withdrawal due to pregnancy are limited. The aim of the study was to evaluate the frequency and predictors of disease reactivation in patients who stopped FTY for pregnancy. A multicentre retrospective cohort study was conducted in four Italian MS centres in 2013-2019.

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Tumour Necrosis Factor alpha (TNFα) blockers are common and effective treatments for several autoimmune diseases but can be associated with neuroinflammatory events. We describe the disease course of ten patients who developed CNS demyelinating events while exposed to TNFα blockers. We divided them into two groups: eight patients with Relapsing Multiple Sclerosis and two isolated optic neuritis.

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Neurological sequelae of SARS-CoV-2 infection have already been reported, but there is insufficient data about the impact of the pandemic on the management of the patients with chronic neurological diseases. We aim to analyze the effect of COVID-19 pandemic and social restriction rules on these fragile patients. Patients with chronic neurologic diseases routinely followed at the outpatient clinic of Gemelli University Hospital, Rome, were assessed for symptoms suggestive of SARS-CoV-2 infection in the pandemic period, consequences of social restrictions, and neurological disease features, concomitant medical conditions, current medical and disease-specific treatments.

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