Publications by authors named "Giorgia Buoncuore"
Article Synopsis
- This study examined how caffeine affects endothelial function in patients with Systemic Lupus Erythematosus (SLE) by looking at circulating endothelial progenitor cells (EPCs).
- Researchers found a positive relationship between caffeine intake and the percentage of circulating EPCs in SLE patients, suggesting that caffeine may enhance endothelial function.
- In vitro experiments showed that adding caffeine to EPCs treated with SLE sera improved their survival, morphology, and ability to form colonies, primarily by reducing apoptosis and increasing autophagy through a specific cellular pathway.
Objectives: To investigate the expression of citrullinated and carbamylated proteins in extracellular microvesicles (EMVs) from RA patients.
Methods: We enrolled 24 RA naïve for biological therapy and 20 healthy donors (HD), matched for age and sex. For each patient, laboratory and clinical data were recorded and clinical indexes were measured (Clinical Disease Activity Index, Simplified Disease Activity Index, DAS28).
Autophagy is a homeostatic process responsible for the self-digestion of intracellular components and antimicrobial defense by inducing the degradation of pathogens into autophagolysosomes. Recent findings suggest an involvement of this process in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the role of autophagy in the immunological mechanisms of coronavirus disease 2019 (COVID-19) pathogenesis remains largely unexplored.
View Article and Find Full Text PDFfolliculogenesis (F) has been proposed as an emerging technology to support follicle growth and oocyte development. It holds a great deal of attraction from preserving human fertility to improving animal reproductive biotechnology. Despite the mice model, where live offspring have been achieved,in medium-sized mammals, F has not been validated yet.
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