Perspectives and Behaviors of People with Diabetes toward Time in Range and Glucose Control in Diabetes Management: An Online Survey.

Introduction: This study assessed experiences, attitudes, and behaviors of people with diabetes (PwD) regarding diabetes self-management and glucose control, and their level of awareness, knowledge, and attitudes toward time in range (TIR).

Methods: This quantitative survey was conducted using an online questionnaire across seven countries. Respondents were PwD classified into three subgroups: type 1 (T1), type 2 insulin (T2 insulin), and type 2 not on insulin (T2 N/insulin).

Healthcare Professionals' Knowledge of and Attitudes Towards the Use of Time in Range in Diabetes Management: Online Survey Across Seven Countries.

Introduction: Time in range (TIR) is a metric of glycaemic target management derived from continuous glucose monitoring (CGM) data. This study aimed to understand knowledge of and attitudes towards use of TIR among healthcare professionals (HCPs), and gain insights into benefits and barriers to its use in clinical practice.

Methods: An online survey was disseminated across seven countries.

Chronic Opisthorchis felineus infection attenuates atherosclerosis--an autopsy study.

Previously, we proposed a hypothesis that chronic helminthic infection may have beneficial effects on the development of atherosclerosis. The aim of this study was to investigate an association between Opisthorchis felineus chronic helminthic infections with aortic atherosclerosis and serum total cholesterol. A series of medico-legal autopsy specimens collected in Khanty-Mansiisk (the region in Russia endemic for O.

A patient and physician survey of fibromyalgia across Latin America and Europe.

Background: Patients and physicians from three Latin American (LA) and six European countries were surveyed in order to describe differences in journey to diagnosis, impact, and management of fibromyalgia (FM).

Methods: 900 patients (300 LA; 600 Europe) and 1824 physicians (604 LA; 1220 Europe) were surveyed between October-December 2010 (LA) and February-April 2008 (Europe). Patients and physicians (GP or specialists) completed separate questionnaires, on symptoms, impact, and FM management.

Sexual Health and Overall Wellness (SHOW) survey in men and women in selected European and Middle Eastern countries.

Objective: To investigate whether better sexual health is associated with improvements in overall health and wellness, a more loving and intimate relationship, and a more positive outlook on life.

Methods: The Sexual Health and Overall Wellness survey used self-administered questionnaires to collect data from men and women aged 25-74 years who had had sexual intercourse at least once within the previous 12 months.

Results: Across nine countries, 3780 self-administered questionnaires were completed: 1893 from men (mean age, 44.

Survey of physician experiences and perceptions about the diagnosis and treatment of fibromyalgia.

Background: Fibromyalgia (FM) is a condition characterized by widespread pain and is estimated to affect 0.5-5% of the general population. Historically, it has been classified as a rheumatologic disorder, but patients consult physicians from a variety of specialties in seeking diagnosis and ultimately treatment.

A patient survey of the impact of fibromyalgia and the journey to diagnosis.

Background: Fibromyalgia is a painful, debilitating illness with a prevalence of 0.5-5.0% that affects women more than men.

[The biorhythmology of primary and superinvasive opisthorchiasis. The seasonal variability in the relative mass of the parenchymatous and lymphoid organs in golden hamsters].

600 Golden Hamsters were divided into 3 groups: 1--free from opisthorchis invasion, 2--once infected, 3--repeatedly infected. Seasonal variability of liver, portal and mesentery lymph node and adrenal gland relative mass was investigated in winter, spring and autumn. Diurnal stereotype variability of parenchymatous and lymphoid organ relative mass is associated with a season and invasion number, and in a considerable degree is reflected in the meaning of average diurnal index.

[The biorhythmology of primary and superinvasive opisthorchiasis. Seasonal changes in the circadian activity of the cyclic nucleotides and of the key enzyme of the pentosephosphate cycle (G-6-PD) in the peripheral blood of golden hamsters].

570 males of golden hamsters were divided into 3 groups: I--free from invasion, II--once infected, III--repeatedly infected. Diurnal activity of cyclic nucleotides and enzyme of pentose-phosphate cycle (G-6-PhDG) was investigated in spring, autumn, and winter at 3, 7, 11 a.m.

[The biorhythmology of primary and superinvasive opisthorchiasis. The seasonal changes in the circadian activity of the portal (regional) lymph node in golden hamsters].

540 male golden hamsters were divided into 3 groups: I--free from invasion, II--once infected, III--repeatedly infected. Diurnal activity of portal lymph node immunocompetent cells was investigated in spring, autumn and winter at 3, 7, 11 a. m.

[The biorhythmology of primary and superinvasive opisthorchiasis. Seasonal changes in the circadian dynamics of the peripheral blood composition in golden hamsters].

540 golden hamsters were selected into 3 groups: 1--free from invasion, 2--once infected, 3--repeatedly infected with Opisthorchis felineus. Diurnal activity of peripheral blood composition was investigated in spring, autumn and winter at 3, 7, 11 a.m.

[The comparative characteristics of the clinico-immunological indices in different contingents of opisthorchiasis patients in a hyperendemic focus. 4. The transplacental transmission of Opisthorchis felineus antigens].

25 women in labour with chronic opisthorchiasis have been examined. They were representatives of native (7), local (8) and migrated population of the focus. Control group comprised 10 women from the local population free of invasion.

[The dynamics of the liver calcium-binding protein in golden hamsters with opisthorchiasis].

By means of immunochemical methods a considerable increase in Ca(2+)-transporting glycoprotein (GP) in liver tissues of golden hamsters at early stages of opisthorchiasis has been established. On the 3rd day after the infection GP amount increases 6 fold, on the 7th day--15 fold. On the 14th day GP amount decreases but does not reach the control level.

[The decreased susceptibility of Syrian hamsters to Opisthorchis felineus invasion after its repeated administration].

The investigations conducted on Syrian hamsters have revealed that multiple enteral infusions of cold inactivated (t = -10 degrees C) O. felineus metacercariae resulted in the formation of immunocompetent cell and fibroblast infiltrations around the branches of the portal vein. The infestation of animals by viable pathogens led to reduced accommodation of helminths and suppressed cell infiltration in the liver.

[Effect of an Opisthorchis infestation on implantation growth of the liver epithelium].

The features of proliferation and differentiation of the liver ductular epithelium from animals infected with opisthorchis were specified in experimental implantation growth. They manifested themselves in disorders of the mitotic regimen and intercellular interactions, in atypical proliferations and primary glandular metamorphism of regenerating cells.

[Circadian rhythm of liver phospholipids in the normal golden hamster and in opisthorchiasis].

Circadian rhythms of total phospholipids, individual fractions of phosphatide acid, cardiolipin, phosphatidyl ethanolamine, phosphatidylcholine, sphingomyelin, and lysolecithins in the liver of golden hamsters infected with opisthorchiasis (days 30 and 150 of invasion) and freed from helminths (day 92 after dehelminthization) are desynchronized in phase, amplitude and level.