Topographical distribution of typical unifocal congenital hypertrophy of retinal pigment epithelium.

Purpose: To describe the topographical distribution of typical congenital hypertrophy of retinal pigment epithelium (CHRPE) lesions in the ocular fundi.

Methods: Retrospective review of the clinical records of 52 patients with typical unifocal CHRPE.

Results: The 52 CHRPE lesions ranged from 2.

A modified method for determining protein binding capacity of plant polyphenolics using radiolabelled protein.

A modified radiochemical protein binding method for determining the protein binding capacity of plant polyphenolics (tannins) is described. Purified tannin or unfractionated plant extracts were immobilised on filter paper discs and incubated with the 125I-labelled bovine serum albumin. Protein bound to the disc was proportional to the amount of tannin applied to the disc, although at high concentrations of polyphenolics the discs became saturated and the relationship was no longer applicable.