Publications by authors named "Gina S Perez Giraldo"
Article Synopsis
- The study explores the neurological effects of SARS-CoV-2 infection in two groups: post-hospitalized patients (PNP) and non-hospitalized patients (NNP), across different age ranges.
- It analyzed data from 200 PNP and 1,100 NNP patients evaluated at a specialized clinic between May 2020 and March 2023, focusing on how age influences neurological symptoms and quality of life.
- Findings showed that younger adults had higher reported fatigue, sleep disturbances, and poorer executive function compared to older individuals, who exhibited a lower prevalence of Neuro-PASC symptoms despite having more comorbidities.
Long COVID, also called post-acute sequelae of SARS-CoV-2 infection (PASC) affects millions of people in the world. The neurologic manifestations of PASC (Neuro-PASC) are among the most debilitating but they are largely unreported in Africa. We sought to compare the demographics, symptoms and cognitive profile of post-hospitalization Neuro-PASC (PNP) and non-hospitalized Neuro-PASC (NNP) patients in Nigeria.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to evaluate the long-term effects of COVID-19 on neurological symptoms, cognitive function, and quality of life in Colombian patients experiencing neurological post-acute sequelae (Neuro-PASC).
- Researchers analyzed data from 100 patients (50 post-hospitalization and 50 non-hospitalized) who had persistent symptoms for over 6 weeks, highlighting common symptoms like brain fog, fatigue, and anxiety.
- Results indicated that both groups had impaired quality of life and cognitive function, with recommendations for early detection and support for Neuro-PASC patients to address these ongoing challenges.
Background: Autoimmune diseases can coexist with immunodeficiency. We describe a treatment approach in which granulocyte-colony stimulating factor (G-CSF) is used to restore immune competence without worsening autoimmunity. G-CSF is a polyfunctional cytokine that influences survival, proliferation, and differentiation of hematopoietic stem cells, and has immunomodulatory effects on the innate and adaptive immune systems.
View Article and Find Full Text PDFPurpose Of Review: Tumor-like brain lesions are rare and commonly suggest a neoplastic etiology. Failure to rapidly identify non-neoplastic causes can lead to increased morbidity and mortality. In this review, we describe 10 patients who presented with atypical, non-neoplastic tumor-like brain lesions in which brain biopsy was essential for a correct diagnosis and treatment.
View Article and Find Full Text PDFSARS-CoV-2-Specific Immune Responses in Patients With Postviral Syndrome After Suspected COVID-19.
Neurol Neuroimmunol Neuroinflamm
November 2023
Background And Objectives: Millions of Americans were exposed to SARS-CoV-2 early in the pandemic but could not get diagnosed with COVID-19 due to testing limitations. Many have developed a postviral syndrome (PVS) including neurologic manifestations similar to those with postacute sequelae of SARS-CoV-2 infection (Neuro-PASC). Owing to those circumstances, proof of SARS-CoV-2 infection was not required for evaluation at Northwestern Medicine's Neuro COVID-19 clinic.
View Article and Find Full Text PDFObjective: To characterize neurologic manifestations in post-hospitalization Neuro-PASC (PNP) and non-hospitalized Neuro-PASC (NNP) patients.
Methods: Prospective study of the first 100 consecutive PNP and 500 NNP patients evaluated at a Neuro-COVID-19 clinic between 5/2020 and 8/2021.
Results: PNP were older than NNP patients (mean 53.
Objective: We characterized the evolution of neurologic symptoms and self-perceived recovery of non-hospitalized COVID-19 "long haulers" 6-9 months after their initial Neuro-COVID-19 clinic evaluation.
Methods: In this follow-up study on the first 100 patients, 50 SARS-CoV-2 laboratory-positive (SARS-CoV-2 ), and 50 laboratory-negative (SARS-CoV-2 ), evaluated at our Neuro-COVID-19 clinic between May and November 2020, patients completed phone questionnaires on their neurologic symptoms, subjective impression of recovery and quality of life.
Results: Of 52 patients who completed the study (27 SARS-CoV-2 , 25 SARS-CoV-2 ) a median 14.
Immune-Mediated Disorders Affecting the Spinal Cord and the Spine.
Curr Neurol Neurosci Rep
January 2021
Purpose Of Review: To review the most recent advances and provide a description of the most common autoimmune diseases causing myelitis and selective spine disorders. The ultimate goal of this article is to facilitate the prompt recognition of these diseases.
Recent Findings: The recent discovery of biomarkers such as aquaporin 4 (AQP4) and myelin oligodendrocyte glycoprotein (MOG) antibodies has changed our understanding of autoimmune diseases affecting the spinal cord as well as their treatment and outcomes.