Chemical Elicitors Induce Rare Bioactive Secondary Metabolites in Deep-Sea Bacteria under Laboratory Conditions.

Bacterial genome sequencing has revealed a vast number of novel biosynthetic gene clusters (BGC) with potential to produce bioactive natural products. However, the biosynthesis of secondary metabolites by bacteria is often silenced under laboratory conditions, limiting the controlled expression of natural products. Here we describe an integrated methodology for the construction and screening of an elicited and pre-fractionated library of marine bacteria.

Seroprevalence of spp infection and its risk factors among domestic dogs in Bogotá, Colombia.

Different analytical tools were used to determine the seroprevalence of and risk factors associated with spp infection in 192 domestic dogs () in Bogotá, Colombia. Using the microscopic agglutination test (MAT), a battery of 16 serovars were tested. The seroprevalence of spp was calculated as 36.