Publications by authors named "Gina P Mejia-Abril"
Beneficial effect of temporary methotrexate interruption on B and T cell responses upon SARS-CoV-2 vaccination in patients with rheumatoid arthritis or psoriatic arthritis.
Pedro Martínez-Fleta Esther F Vicente-Rabaneda Ana Triguero-Martínez Emilia Roy-Vallejo Miren Uriarte-Ecenarro
NPJ Vaccines
January 2024
Article Synopsis
- A study evaluated the immune response of rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients to COVID-19 vaccines after stopping methotrexate (MTX) treatment for 1 or 2 weeks compared to those who continued MTX.
- Patients who paused MTX showed higher levels of antibodies and a stronger T-cell response, particularly in the group that withdrew for 2 weeks.
- Importantly, stopping MTX did not lead to increased flare-ups of RA or PsA, suggesting that a temporary withdrawal could enhance vaccine effectiveness without risking disease stability.
Efficacy and safety of preoperative preparation with Lugol's iodine solution in euthyroid patients with Graves' disease (LIGRADIS Trial): Study protocol for a multicenter randomized trial.
José Luis Muñoz de Nova Guzmán Franch-Arcas Gina Paola Mejía-Abril María Eugenia Flores-Ruiz Nuria Muñoz-Pérez
Contemp Clin Trials Commun
June 2021
Background: Currently, both the American Thyroid Association and the European Thyroid Association recommend preoperative preparation with Lugol's Solution (LS) for patients undergoing thyroidectomy for Graves' Disease (GD), but their recommendations are based on low-quality evidence. The LIGRADIS trial aims to provide evidence either to support or refute the systematic use of LS in euthyroid patients undergoing thyroidectomy for GD.
Methods: A multicenter randomized controlled trial will be performed.