Trials for preparation and evaluation of a combined inactivated reassorted H5N1 and O157 vaccine in poultry.

Background And Aim: Avian influenza (AI), which is one of the major respiratory diseases of poultry, and () have caused major economic losses around the world, including in Egypt. Therefore, in this study, we aimed to produce a vaccine from O157 and AI H5N1 formulated with Montanide ISA70 for the protection of poultry against both diseases.

Materials And Methods: We divided one hundred 3-week-old chicks into four groups: Group 1 was vaccinated with prepared inactivated AI H5N1formulated with Montanide ISA70, Group 2 was vaccinated with inactivated formulated with Montanide ISA70, Group 3 was vaccinated with combined and AI H5N1 formulated with Montanide ISA70, and Group 4 was an unvaccinated control group.