Publications by authors named "Gina M Butler"
Article Synopsis
- Effective interpretation of genome function now requires understanding the actual roles of cis-regulatory elements (CREs) beyond just mapping them.
- We developed a new technique called HCR-FlowFISH that uses flow cytometry to assess the effects of CRISPR on these CREs by measuring native RNA levels.
- In our study of over 325,000 genetic changes, we discovered that CREs can influence multiple genes simultaneously, bypass nearby genes, and exhibit both activation and silencing roles.
