Publications by authors named "Gilmer Solis Sanchez"

Article Synopsis
  • The study investigates the immunogenic properties of soluble and excretion/secretion antigens from Leishmania braziliensis and Leishmania peruviana to identify potential diagnostic proteins for American Tegumentary Leishmaniasis (ATL).
  • Key findings reveal that the soluble antigen of Leishmania braziliensis has high sensitivity (87.7%) and perfect specificity (100%) for ATL detection, while Leishmania peruviana shows slightly better sensitivity (92.3%) and good specificity (95.7%).
  • The research suggests that using immunoblot techniques can enhance the diagnostic accuracy for ATL, particularly in challenging cases, and emphasizes the need to further characterize the identified immunogenic regions for developing effective recombinant and synthetic proteins
View Article and Find Full Text PDF

Objectives.: Motivation for the study. To understand the characteristics and distribution of the main parasitic zoonoses in Peru and to generate data for decision making in surveillance, prevention and control.

View Article and Find Full Text PDF

The National Institute of Health has, for the first time, identified National Priorities for Oral Health Research, this process was carried out by the Subdirectorate of Research and Laboratories of Noncommunicable Diseases of the National Center for Public Health with the technical advice of the Directorate of Research and Innovation in Health and in coordination with the Executive Directorate of Oral Health of the General Directorate of Strategic Interventions in Public Health of the Ministry of Health, using a participatory methodology with three key actors: researchers/specialists, experts and decision-makers. This article aims to describe the process used to identify these priorities, which consisted of five phases: i) identification of the strategic objectives of the Ministry of Health, ii) identification of needs in oral health research, iii) review by experts and assessment of needs according to criteria and v) presentation of the priorities. As a result, 12 priorities were obtained, which were subsequently approved by Ministerial Resolution No.

View Article and Find Full Text PDF

Objective.: To describe the iron status profile and to propose hemoglobin adjustment factors for altitude for children aged 6 to 8 months in Lima, Arequipa, Cusco and Puno.

Materials And Methods.

View Article and Find Full Text PDF

Objectives: . To evaluate the IgG antibody response by ELISA using Wuhan and Lambda antigens in health care workers with and without history of SARS-CoV-2 infection prior to immunization with the first and second doses of Sinopharm vaccine (BBIBP-CorV).

Materials And Methods: .

View Article and Find Full Text PDF

Background: The administration of a third (booster) dose of COVID-19 vaccines in Peru initially employed the BNT162b2 (Pfizer) mRNA vaccine. The national vaccination program started with healthcare workers (HCW) who received BBIBP-CorV (Sinopharm) vaccine as primary regimen and elderly people previously immunized with BNT162b2. This study evaluated the reactogenicity and immunogenicity of the "booster" dose in these two groups in Lima, Peru.

View Article and Find Full Text PDF

Objective: To identify the factors associated with the use of the N95 respirator in Nursing and Medical students in the daily life of the covid-19 pandemic.

Methods: Descriptive-analytical cross-sectional study carried out in 2020. A total of 830 students from three universities in Peru participated in the study.

View Article and Find Full Text PDF

Objectives: To standardize and validate an in-house RT-LAMP test for the detection of SARS-CoV-2, based on laboratory and field assays using samples from COVID-19 suspected patients.

Materials And Methods: An in-house SARS-CoV-2 RT-LAMP molecular test was standardized, establishing the detection limit with Vero cells of isolated Peruvian strains of SARS-CoV-2, and the robustness to various concentrations of primers. The laboratory validation was performed with 384 nasal and pharyngeal swab samples (UFH) obtained between March and July 2020.

View Article and Find Full Text PDF

The study aimed to describe the characteristics of SARS-CoV-2 transmission among members of households with a confirmed primary case of COVID-19 in districts with low burden of cases in Lima, Peru, compared to a district with high burden. This was a retrospective study with a secondary database review. Information was collected from an epidemiological surveillance activity in close contacts (household members) in 52 households in Lima, with a single member with COVID-19.

View Article and Find Full Text PDF

A descriptive observational study was carried out to identify the characteristics of the oncological clinical trials submitted to the Instituto Nacional de Salud del Perú during the period from 1995 to 2019. The information was obtained from the Peruvian Registry of Clinical Trials. We identified 1,996 clinical trials during the studied period, from which 470 were oncological (23.

View Article and Find Full Text PDF