IgG Isotypes Targeting a Recombinant Chimeric Protein of Trypanosoma cruzi in Different Clinical Presentations of Chronic Chagas Disease.

Chagas disease (CD) is caused by the protozoan Trypanosoma cruzi, which leads to a spectrum of clinical presentations that range from asymptomatic to severe cardiac involvement. The host immune response plays a pivotal role in disease progression. Ig isotypes may contribute to disease pathogenesis.

Natural infection of Lutzomyia longipalpis (Lutz & Neiva, 1912) by Leishmania infantum in a municipality with a high incidence of visceral leishmaniasis in the Brazilian Midwest.

Background: Here, Leishmania presence in sand flies from Três Lagoas, Mato Grosso do Sul, Brazil, after visceral leishmaniasis (VL) was investigated.

Methods: In April 2022, two light traps were deployed within and around the residence for two days post-VL case report.

Results: A total of 120 Lutzomyia longipalpis were collected.

Wide distribution of Trypanosoma cruzi-infected triatomines in the State of Bahia, Brazil.

Background: The identification of Trypanosoma cruzi and blood-meal sources in synanthropic triatomines is important to assess the potential risk of Chagas disease transmission. We identified T. cruzi infection and blood-meal sources of triatomines caught in and around houses in the state of Bahia, northeastern Brazil, and mapped the occurrence of infected triatomines that fed on humans and domestic animals.

Seroprevalence of Trypanosoma cruzi infection among blood donors in the state of Bahia, Brazil.

Introduction: Chagas disease (CD) affects 5.7-7.0 million individuals worldwide, and its prevalence reached 25.

TRYPANOSOMA CRUZI AND LEISHMANIA SP. INFECTION IN WILDLIFE FROM URBAN RAINFOREST FRAGMENTS IN NORTHEAST BRAZIL.

:  Trypanosoma cruzi and Leishmania sp. are important protozoan parasites for humans and animals in the Americas, causing Chagas disease and cutaneous or visceral leishmaniasis, respectively. These vector-borne diseases affect permanent and transient populations in developing tropical countries that exhibit favorable conditions for the perpetuation of the parasite cycle.

Frequent house invasion of Trypanosoma cruzi-infected triatomines in a suburban area of Brazil.

Background: The demographic transition of populations from rural areas to large urban centers often results in a disordered occupation of forest remnants and increased economic pressure to develop high-income buildings in these areas. Ecological and socioeconomic factors associated with these urban transitions create conditions for the potential transmission of infectious diseases, which was demonstrated for Chagas disease.

Methodology/principal Findings: We analyzed 930 triatomines, mainly Triatoma tibiamaculata, collected in artificial and sylvatic environments (forests near houses) of a suburban area of the city of Salvador, Bahia State, Brazil between 2007 and 2011.

Vector control measures failed to affect genetic structure of Aedes aegypti in a sentinel metropolitan area of Brazil.

In order to evaluate subpopulation differentiation, effective population size (Ne) and evidence for population bottlenecks at various geographic levels, Aedes aegypti larvae were collected longitudinally from 2007 to 2009 from four areas in the city of Salvador, Brazil. The DNA from each larva was isolated and genotyped with five independent microsatellite markers. FST and Jost's D revealed significant population structuring (P<0.